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Re-evaluating hereditary breast and ovarian cancer risk: clinical impact of u...

Gislinge(JIP),Byrjalsen(A),Naver(KV),Claus... Fam Cancer 2026-03-27

...BRCA2 PV, 55 had PVs in moderate-risk genes, and 277 were enrolled based on family history of OC ± BC alone. Of these 27...

Age-Associated Genetic Variations in Breast Cancer: Somatic Mutations and Co-...

Ekinci(B),Orenay-Boyacioglu(S),Erdogdu(IH)... Biomedicines 2026-02-25

...BRCA2, and KMT2C. Notably, PIK3CA mutations were significantly more frequent in geriatric patients (28.3% vs. 23.2%, p =...

Beyond the Surface: Deciphering the Role of Genetic Susceptibility in BIA-ALC...

Hah(YS),Lee(SJ),Hwang(J),Choi(HY) Biomedicines 2026-03-08

...BRCA2 and HLA associations). Methods: We conducted a narrative, evidence-based synthesis of peer-reviewed epidemiologic ...

STK11 and DNA Repair Gene Mutations Define Hereditary Subset of Middle Easter...

Bu(R),Haqawi(W),Razzaq(EAA),Azam(S),Iqbal(... Int J Mol Sci 2026-03-14

...BRCA2, FANCA, SLX4, RAD50, MSH6, POLD1 and NF1. Four patients (36.4%) carried PVs/LPVs in canonical FA pathway genes; th...

Assessment of Homologous Recombination System Gene Expression in Chemological...

Tsyganov(MM),Bulatova(DZ),Fedorenko(AA),Lo... Curr Issues Mol Biol 2026-03-04

...BRCA2, contributes to genomic instability and the development of more aggressive tumor clones. The use of chemical carci...

Genetic Predisposition to Pancreatic Cancer: A Systematic Review of Hereditar...

Baraian(CS),Turculet(CS),Negoi(I) Cancers (Basel) 2026-03-18

...BRCA2 mutation (up to 22-fold risk), and familial pancreatic cancer with at least three affected relatives (up to 32-fol...

Effects of short- and long-term mutant IDH1 inhibition on radiosensitivity ac...

Kitagawa(Y),Muzyka(LD),Kobayashi(A),Wetzel... Neurooncol Adv None

...BRCA2 mutations, exhibited modest radiosensitization with IDHi. Prolonged AGI-5198 exposure does not reduce IR sensitivi...

Natural menopause, menarche and breast cancer risk in BRCA1 and BRCA2 pathoge...

Mavaddat(N),Barnes(DR),Michailidou(K),Zhao... Br J Cancer 2026-05-00

...BRCA2, but not BRCA1, and between AAM and BC risk in BRCA1 and BRCA2 PV carriers. These results may aid risk prediction ...

Genetic Testing in Breast Cancer: Narrative Review and Clinical Insights.

Bistriceanu(I),Ungureanu(CO),Stoica(RA),Gi... Maedica (Bucur) 2026-03-00

...BRCA2) remain central to hereditary breast and ovarian cancers, progress in cancer genetics has shifted clinical practic...

MMTV Virus Detection, Survival Analysis, and Prognostic Relevance of Six Tumo...

Alamri(S),Awadalla(M),Henawi(RA),Al-Hazzaa... Int J Breast Cancer None

...BRCA2), telomere length maintenance (TERT), DNA damage response (FGFR2), and DNA repair (CHD1) are recognized for their ...

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