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RAD18

Gene name:RAD18 E3 ubiquitin protein ligase

RAD18是RAD基因家族的重要成员,属于E3泛素连接酶家族,在DNA损伤修复和基因组稳定性维持中发挥关键作用。它的主要功能是通过泛素化修饰调控DNA损伤应答,特别是针对复制压力或紫外线等诱发的DNA损伤。RAD18与RAD6形成复合物,共...

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