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Transcription profiling by array of human malignant peripheral nerve sheath tum…

Samples:9 Organism:Homo sapiens Type:transcription profiling by array Oct. 21, 2014

...NF1. NF1 encodes a Ras GTPase-activating protein (RasGAP) and its loss drives cancer by activating Ras4. We show that SU...

PRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-ba…

Samples:6 Organism:Homo sapiens Type:ChIP-seq Oct. 21, 2014

...NF1. NF1 encodes a Ras GTPase-activating protein (RasGAP) and its loss drives cancer by activating Ras4. We show that SU...

CTCR-OV03/CTCR-OV04 ovarian cancer

Samples:138 Organism:Homo sapiens Type:comparative genomic hybridization by ar… Oct. 1, 2014

...NF1 deletion of a relapse case was already present at biopsy. By leveraging the information contained in the evolutionar...

Transformation of quiescent adult oligodendrocyte precursor cells into malignan…

Samples:28 Organism:Mus musculus Type:transcription profiling by array Sept. 9, 2014

...NF1 specifically in adult OPCs, and demonstrated that these cells consistently give rise to malignant gliomas. To invest...

SUZ12 and NF1 loss cooperate to enhance Ras transcriptional output and sensitiz…

Samples:9 Organism:Homo sapiens Type:transcription profiling by array July 1, 2014

...NF1 cooperate in peripheral nervous system tumors, glioblastomas, and melanomas. NF1 encodes a Ras GTPase-activating pro...

Defining key signaling nodes and therapeutic biomarkers in NF1-mutant cancers

Samples:8 Organism:Mus musculus Type:transcription profiling by array July 1, 2014

The NF1 tumor suppressor encodes a RAS GTPase-Activating Protein (RasGAP). Accordingly, deregulated RAS signaling under...

SVA retrotransposon insertion-associated deletion represents a novel mutational…

Samples:24 Organism:Homo sapiens Type:comparative genomic hybridization by ar… May 29, 2014

...NF1 deletions under investigation 12 atypical NF1 deletions were investigated with the custom array CGH

Array CGH of cutaneous neurofibromas (cNFs) from NF1 patients

Samples:36 Organism:Homo sapiens Type:comparative genomic hybridization by ar… May 28, 2014

...NF1 patients 9 cNFs and matched DNA samples were hybridised to the SurePrint G3 human 400k CGH microarray

Human non-GCIMP gioblastoma subtypes evolve from a common proneural-like precur…

Samples:144 Organism:Homo sapiens, Mus musculus Type:transcription profiling by array April 3, 2014

...Nf1, shp53 or shNf1+shp53 and the gene expression profiles of the shNf1, shp53 or shNf1/p53 cells were then compared to ...

MIRnome Profiling of Hereditary Pheochromocytoma and Paraganglioma Reveals Spec…

Samples:54 Organism:Homo sapiens Type:transcription profiling by array July 2, 2013

...NF1, and TMEM127 genes through microarray analysis. We identified microRNA signatures specific to, as well as common amo...

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