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TECTAL GLIOMA VERSUS PILOCYTIC ASTROCYTOMA: REVISITING TUMOR CLASSIFICATION IN …

Samples:27 Organism:Yersinia enterocolitica, Eukaryota, Cam… Type:methylation profiling by array Aug. 19, 2026

...NF1 mutations and BRAF mutations. Furthermore, when we compared the epigenetic profile of our tumors with those availabl...

Deciphering cellular and molecular signatures of malignant progression in Neuro…

Samples:20 Organism:Mus musculus, Mus musculus Type:RNA-seq of coding RNA from single cells Aug. 26, 2025

...NF1). NFs are benign nerve sheath tumors due to bi-allelic loss of NF1, encoding a negative regulator of Ras pathway, in...

RNAseq of GBM tumors with SAT1 knockout

Samples:10 Organism:Mus musculus, Mus musculus Type:RNA-seq of coding RNA March 20, 2025

...NF1 knockout) and performed RNAseq.

Multiomics of three distinct hematological malignancies in a patient reveals th…

Samples:39 Organism:Homo sapiens, Homo sapiens Type:spatial transcriptomics by high-through… March 17, 2023

...NF1 and KMT2D mutations and a complex karyotype. Furthermore we demonstrated that spatial transcriptomics can identify t...

Mutations in RAS pathway induce synthetic lethality of MEK inhibition with mito…

Samples:12 Organism:Homo sapiens, Homo sapiens Type:transcription profiling by array Feb. 22, 2022

...NF1 knockout and NRAS G12D, that induce the RAS signalling pathway were made in TF1 cells. The NRAS G12D mutant was trea...

Kinome and Rho-GTPase Synthetic Lethal shRNA Library Screen in paired NF1-/- a…

Samples:12 Organism:Homo sapiens Type:DNA-seq Nov. 30, 2019

To identify possible novel targets for the treatment of plexiform neurofibroma formation through a synthetic lethal shRN...

Methylation profiling of adult astroblastoma

Samples:6 Organism:Homo sapiens Type:methylation profiling by array March 22, 2019

...NF1 mutations) were present in 10 of 15 patients and overrepresented in the HGG group (3/5) compared to previously repor...

Expression data of three sets of cells: (1) Schwann cells and macrophages from …

Samples:23 Organism:Mus musculus Type:transcription profiling by array May 1, 2017

...Nf1-/-) and macrophages (Nf1+/+) from 1-month-old neurofibroma, (3) Schwann cells (Nf1-/-) and macrophages (Nf1+/+) fr...

Expression profiling of primary glioma samples

Samples:22 Organism:Homo sapiens Type:transcription profiling by array Oct. 30, 2015

...NF1 (NF1-M), Sprouty (SPRY-M) and PTEN (PTEN-M) in gliomas. Their signatures enabled robust clustering of adult diffuse ...

Decoding NF1 intragenic copy number changes

Samples:6 Organism:Homo sapiens Type:comparative genomic hybridization by ar… July 30, 2015

...NF1 gene. However, no clear genotype-phenotype correlations could be identified among the NF1 patients carrying NF1 intr...

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