...NF1) is a multi-system disease caused by mutations in the NF1 gene encoding a Ras-GAP protein, neurofibromin, which nega...
...NF1 null states are present in 7/95=7% of adult AML and delineate a disease subset that could be preferentially targeted...
...NF1 (both myxofibrosarcoma and pleomorphic liposarcoma). We show evidence that PIK3CA mutations, found in 18% of myxoid/...
...NF1 (both myxofibrosarcoma and pleomorphic liposarcoma). We show evidence that PIK3CA mutations, found in 18% of myxoid/...
...NF1 microdeletion patients, non-deleted NF1 patients (i.e. patients with an intragenic NF1 mutation) were also selected ...
...NF1 patients 24 MPNSTs and 3 NF samples were hybridised to the human 32K BAC tiling path array
...NF1-C2. The human breast tumor cell line MDA-MB-436 were stably transfected with an expression plasmid including NF1-C2....
Understanding biological pathways critical for common neurofibromatosis type 1 (NF1) peripheral nerve tumors is essentia...
...NF1). While no expression signature was found that; could discriminate clinically-aggressive or recurrent tumors from mo...
Comparison of the changes in the gene expression profile of cells in which NF1 has been knocked down by RNAi in the pres...
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