...APLP2-DKO mice shows striking differences as compared to APP/APLP2-DKO mice. Unexpectedly, APLP1/APLP2-DKO mice exhibit ...
...APLP2. To examine the distribution of APLP2 in the nervous system, we generated antibodies specific for APLP2 and used t...
...APLP2. The present study examines the metabolism of mouse APLP2 in cultured mammalian cells. We report that in stably tr...
...APLP2 in cancer progression, the exact role of APLP2 in cell migration remains elusive. Here in this report, we show tha...
...APLP2 binds, in varied degrees, to several other mouse MHC class I allotypes and that the ability of APLP2 to affect cel...
...APLP2), and its highly homologous family member amyloid precursor protein (APP), have been linked to cellular growth. AP...
...APLP2 shedding in vitro. APLP2 was constitutively shed and released into culture medium in SV40-immortalized human corne...
...APLP2 transmembrane domain. Determination of the APLP2 cleavage sites enables functional studies of the different APLP2 ...
...APLP2 and APLP1. To examine the function of APLP2 in vivo, we generated APLP2 knockout (KO) mice. They are of normal siz...
...APLP2) is aberrantly expressed in pancreatic cancer. Here we showed that APLP2 is increased in pancreatic cancer metasta...
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