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Absence of glomerular IgA1 deposition despite overexpression of galactose-defic…

Wu(J),Xie(T),Zhang(Z),Liu(X),Zhou(X),Zhang(Y… Kidney Int 2026-09-00

...C1galt1) to elevate Gd-IgA1 levels in mice and examine its role in glomerular deposition. We previously established a mo...

Hemocyte-secreted papilin bearing mucin-type O-glycans regulates peripodial sta…

Fuwa(TJ),Itoh(K),Ichimiya(T),Akimoto(Y),Nish… iScience 2026-03-20

...C1GalT1). Loss of C1GalT1 leads to developmental defects across organisms. We previously found that Drosophila C1GalT1 m...

Investigating autoimmunity in the etiology of premature ovarian insufficiency i…

Kuscu(N),Appeltant(R),Petrovic(S),Williams(S… J Reprod Immunol 2026-06-00

...C1galt1), develops early-onset POI and offers a valuable system to investigate causes. This study explored whether autoi...

Multifaceted intestinal defense following experimental blunt abdominal trauma.

Meisen(S),Rayatdoost(F),Oßwald(K),Palmer(A),… Eur J Trauma Emerg Surg 2026-03-17

...C1GALT1 were elevated. In addition, the antimicrobial peptide CRAMP was upregulated in jejunal tissue following injury. ...

Cosmc loss induces truncated O-glycosylation and accelerates Kras-driven pancre…

Mercanoglu(B),Schraps(N),Giannou(AD),Zhou(J)… Neoplasia 2026-07-31

...C1galt1c1), the obligate molecular chaperone for T-synthase (C1galt1), in a pancreas-specific Kras-driven mouse model. A...

Diagnostic Potential of Tn-MUC1 in Breast Cancer: A Novel Immunohistochemical M…

Shimizu(A),Hatanaka(KC),Nange(A),Okumura(A),… Lab Invest 2026-03-00

...C1GALT1), an enzyme involved in galactosylation of the Tn antigen, significantly influenced the cellular localization of...

CD276 immature glycosylation drives colorectal cancer aggressiveness and T cell…

Soares(J),Ferreira(D),Miranda(A),Gonçalves(M… Cell Commun Signal 2026-01-20

...C1GALT1 or C1GALT1C1 defined an immature O-glycosylation phenotype associated with poor prognosis. Glycomic profiling re...

Inhibition of p65 NF-κB enhances production of galactose-deficient IgA1 through…

Person(T),Phillips(M),Rice(T),Hall(S),Julian… bioRxiv 2026-05-05

...C1GALT1, suggesting that NF-κB pathway affects IgA1 O-glycosylation via SP1 transcriptional control of C1GALT1 expressio...

Dismissing-then-recruiting: a unique mechanism for symbiont recruitment and lig…

Xiang(FM),Tang(XT),Brandón(MG),Henawy(AR),Ji… Microbiome 2026-06-09

...C1galt1, GlcAT-P, FUT8/11) were significantly upregulated in the posterior midgut (17-19 TPM), representing a 4-fivefold...

Galacto-Oligosaccharides Reshape Mucin O-Glycan Profiles to Enhance Small Intes…

Xu(L),Li(X),Fan(W),Sun(W),Meng(C),Liu(L),Vog… J Agric Food Chem 2026-06-24

...C1GALT1, GALNTs, and ST3GALs, and downregulation of ST6GALNACs and neuraminidases. Lectin staining further confirmed enh...

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