...Rad17 and Rhino to the 9-1-1 complex, suggesting a structural transition from the Rad17-9-1-1 complex to the Rhino-9-1-1...
...RAD17) and effectors across the MMR, NER, HR, and NHEJ pathways. This impaired genomic surveillance was accompanied by p...
...RAD17/-, FEN1-/-, and POLB-/- cells exhibited hypersensitivity to all these drugs. Consistently, these mutant cells exhi...
...RAD17 rs1045051 GT/GG genotype conferred a higher relapse risk; and BRCA1 rs1799949 GA/AA genotype as a protective facto...
...RAD17-RFC in humans) similarly lacks DNA unwinding activity, restricting loading of 9-1-1 clamp to larger gaps (≥6 nt). ...
...RAD17, LRP8, SMARCA2, EHD1, LEF1 and EIF4G2. Survival analysis using the KM-Plotter platform revealed that YBX3 and amph...
...RAD17. Clonogenic assays in RAD17 knockdown cell lines identified a substantial shift in sensitivity to checkpoint kinas...
...RAD17, the RAD9-RAD1-HUS1 complex, ATR/ATRIP and TopBp1. However, how these proteins involved act in concert with one an...
...Rad17, Ddc1 and Mec3 (known as '9-1-1' in other organisms) and a component of the clamp loader, Rad24 (known as Rad17 in...
...RAD17 promoters leads to the inhibition of their expression. BRCA1 and RAD17 mRNA expression is reduced in HNSCC patient...
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