...RAD50, BLM, NF1, AR, BRCA2, and KMT2C. Notably, PIK3CA mutations were significantly more frequent in geriatric patients ...
...RAD50, MSH6, POLD1 and NF1. Four patients (36.4%) carried PVs/LPVs in canonical FA pathway genes; this increased to five...
...Rad50, Rad51, Brca1, Brca2, and Pold4. Two genes, Rad52 and Bard1, exhibited increased expression levels. It was shown t...
...Rad50-Nbs). Loss of Rad50 disrupts histone modification patterns and causes inappropriate reactivation of embryonic gene...
...RAD50-NBS1 (MRN) complex levels, and phenocopies hypomorphic MRE11 mutations. MRE11pPAS-/- cells exhibit ectopic DNA rep...
...RAD50, a key DNA repair gene. Post-transcriptional regulation led to an increase in RAD50 protein, which facilitated the...
...Rad50, NBS1, MRE11, XRCC1, LIG3, et al. Together, our findings suggest that miR-142-3p plays a radioresistant role in co...
...RAD50-NBS1 (MRN) complex that senses DNA double-strand breaks (DSBs) and coordinates DNA damage response, including ATM ...
...RAD50, and NBN, and PD risk, along with corresponding mRNA expression and DNA repair capacity. A total of 123 clinically...
...RAD50, suggesting that HPRT mutation may influence DNA damage response pathways. Our findings indicate that chronic expo...
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