Cousins(SL),Dai(W),Stephenson(FA) J Neurochem 2015-06-00

...APLP2 with GluN2A- and GluN2B-containing NMDA receptors. Furthermore, similarly to APP, APLP1 and APLP2 both enhanced Gl...

Truong(PH),Ciccotosto(GD),Merson(TD),Spoerri… Glia 2019-00-00

...APLP2) in myelination using APP and APLP2 knockout (KO) mice. Given that BACE1 regulates myelination and myelin sheath t...

Johnston(JA),Norgren(S),Annerén(G),Cowburn(R… Brain Res Mol Brain Res 1996-12-31

...APLP2 were seen in human post-mortem cerebral cortex and cerebellum. Levels of APP and APLP2 mRNA were highest in the te...

Suzuki(T),Ando(K),Isohara(T),Oishi(M),Lim(GS… Biochemistry 1997-04-15

...APLP2, are members of a gene family which include the Alzheimer beta-amyloid precursor protein (APP). APLP1, APLP2, and ...

Siemes(C),Quast(T),Kummer(C),Wehner(S),Kirfe… Exp Cell Res 2006-07-01

...APLP2. In the mammalian epidermis, only APP and APLP2 are expressed. APP and APLP2-deficient mice die shortly after birt...

Gersbacher(MT),Goodger(ZV),Trutzel(A),Bundsc… PLoS One 2013-00-00

The amyloid precursor protein (APP) as well as its homologues, APP-like protein 1 and 2 (APLP1 and APLP2), are cleaved b...

Kaden(D),Voigt(P),Munter(LM),Bobowski(KD),Sc… J Cell Sci 2009-02-01

...APLP2 are mostly found in intracellular compartments. Homo- and heterotypic cis interactions of APP family members could...

Fanutza(T),Del Prete(D),Ford(MJ),Castillo(PE… Elife 2015-11-09

...APLP2) also binds the synaptic release machinery. Deletion of APP and APLP2 produces synaptic deficits similar to those ...

Sandbrink(R),Masters(CL),Beyreuther(K) Biochim Biophys Acta 1994-09-13

We present the cDNA sequence of the rat amyloid precursor-like protein 2 (APLP2) comprising the complete coding sequence...

Liu(K),Wei(C),Yu(H),Zhang(Q),Du(Z) Heliyon 2024-03-15

...APLP2 mRNA via m6A modification, thereby promoting pancreatic cancer progression. These results indicate that HMGA2/IGF2...