...RAD17 double knockout (blm/rad17) cells using chicken DT40 cells. The blm/rad17 cells showed exaggerated growth defects ...
...Rad17, two other Chk1 regulators at stressed replication forks, are also implicated in PCNA ubiquitination. These findin...
...Rad17-RFC, the Rad9-Rad1-Hus1 complex, TopBP1 and Claspin. Rad17 is required for loading of Rad9-Rad1-Hus1 (9-1-1) onto ...
...Rad17 (human Rad9-Hus1-Rad1: 9-1-1) is loaded around effector DNA and thereby activates Mec1 kinase. Dpb11 (Schizosaccha...
...Rad17, which acts as a haploinsufficient tumor suppressor that responds to oncogenic stress and whose loss is associated...
...Rad17) and Fanconi anaemia complementation group D2 protein (FancD2). In addition, we have mapped the ATR-binding region...
...rad17 double mutant. In contrast, AtTSO2 transcription is only activated in response to double-strand breaks (BLM), and ...
...RAD17, BRCA1, BCCIP, KPNA2, RAD1). Also, rOvUS down-regulated the cell proliferation marker gene MKI67, which is absent ...
...Rad17-Mec3 in S. cerevisiae) executes two distinct checkpoint functions. In S. cerevisiae, DNA-bound 9-1-1 directly acti...
...RAD17 restored the original phenotype. Therefore, activation of the meiotic recombination checkpoint, which arrests meio...
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