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DNA-damage tolerance mediated by PCNA*Ub fusions in human cells is dependent on…

Qin(Zhoushuai),Lu(Mengxue),Xu(Xin),Hanna(Mic… Nucleic Acids Res 2013-10-28

...Rev1, another TLS polymerase serving as a scaffold for the assembly of the TLS complex, completely abolished PCNA•Ub-med...

Rev1 is essential in generating G to C transversions downstream of the Ung2 pat…

Krijger(Peter Hugo Lodewijk),Tsaalbi-Shtylik… Eur J Immunol 2013-12-11

...Rev1, we studied WT, Rev1-deficient, Msh2-deficient, and Rev1, Msh2 double-deficient B cells. Loss of Rev1 only slightly...

BRCA1 promotes the ubiquitination of PCNA and recruitment of translesion polyme…

Tian(Fen),Sharma(Shilpy),Zou(Jianqiu),Lin(Sh… Proc Natl Acad Sci U S A 2013-11-11

...Rev1, to the lesions through protein-protein interactions. Our data suggest that BRCA1 plays a critical role in promotin...

The mechanism of nucleotide excision repair-mediated UV-induced mutagenesis in …

Kozmin(Stanislav G),Jinks-Robertson(Sue) Genetics 2013-08-15

...Rev1, PCNA, Rad18, Pol32, and Rad5) and in the early steps of the DNA-damage checkpoint response (Rad17, Mec3, Ddc1, Mec...

Structure and functional analysis of the BRCT domain of translesion synthesis D…

Pryor(John M),Gakhar(Lokesh),Washington(M To… Biochemistry 2013-03-05

...rev1-1 allele encodes a mutant form of Rev1 with a G193R substitution in this domain, which reduces the level of DNA dam...

FANC pathway promotes UV-induced stalled replication forks recovery by acting b…

Renaud(Emilie),Rosselli(Filippo) PLoS One 2013-07-08

...Rev1, the double-strand break repair (DSB)-associated protein MDC1 and the FANC pathway. We describe three novel functio...

REV7 is required for anaphase-promoting complex-dependent ubiquitination and de…

Chun(Abel Chiu-Shun),Kok(Kin-Hang),Jin(Dong-… Cell Cycle 2013-07-16

...REV1. Surprisingly, polyubiquitination of REV1 also requires REV7, a TLS accessory protein that interacts with REV1 and ...

Regulation of error-prone translesion synthesis by Spartan/C1orf124.

Kim(Myoung Shin),Machida(Yuka),Vashisht(Ajay… Nucleic Acids Res 2013-04-17

...Rev1 and the error-prone TLS polymerase Pol ζ, and elevates mutagenesis that relies on POLD3, Rev1 and Pol ζ. These resu...

Analysis of CPD ultraviolet lesion bypass in chicken DT40 cells: polymerase η a…

Varga(Agnes),Marcus(Adam P),Himoto(Masayuki)… PLoS One 2013-06-10

...REV1 protein on the efficiency and mutagenic outcome of TLS. Using mutant chicken DT40 cell lines we show that, on this ...

Ultraviolet radiation effects on the proteome of skin cells.

Muller(H Konrad),Woods(Gregory M) Adv Exp Med Biol 2013-06-18

...Rev1. In the whole animal these events would be associated with inflammation, remodelling of the epidermis and modulatio...

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