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TP53 BRCA1 CRISPR single-cell cancer

Appelgren(Henrik),Kniola(Barbara),Ekwall(Kar… J Cell Sci 2004-06-24

Fission yeast (Saccharomyces pombe) centromere DNA is organized in a central core region flanked on either side by a reg...

Alonso(Alicia),Mahmood(Radma),Li(Shulan),Che… Hum Mol Genet 2004-07-20

Human neocentromeres are fully functional centromeres that provide mitotic stability to rearranged chromosomes that have...

Nakano(Megumi),Okamoto(Yasuhide),Ohzeki(Jun-… J Cell Sci 2004-06-24

To investigate the mechanism of chromatin assembly at human centromeres, we isolated cultured human cell lines in which ...

Tawaramoto(Maki S),Park(Sam-Yong),Tanaka(Yos… J Biol Chem 2004-01-30

The human centromere protein B (CENP-B), a centromeric heterochromatin component, forms a homodimer that specifically bi...

Kuznetsova(I S),Matveev(I V),Podgornaia(O P)… Tsitologiia 2004-02-09

It is considered that centromeric (CEN) regions play the leading role in the formation of chromocentres predominantly co...

Régnier(Vinciane),Novelli(Jacopo),Fukagawa(T… Gene 2004-01-14

Centromere protein A (CENP-A) is a centromere-specific histone H3 variant conserved amongst all eukaryotes. We have isol...

Ashe(Mabelle),Pabon-Peña(Lil),Dees(Ellen),Pr… J Biol Chem 2004-03-03

LEK1, a member of the LEK family of proteins, is ubiquitously expressed in developing murine tissues. Our current studie...

Suzuki(Nobutaka),Nakano(Megumi),Nozaki(Naohi… J Biol Chem 2004-03-30

Recently, human artificial chromosomes featuring functional centromeres have been generated efficiently from naked synth...

Kunitoku(Naoko),Sasayama(Takashi),Marumoto(T… Dev Cell 2004-01-16

The Aurora (Ipl1)-related kinases are universal regulators of mitosis. We now show that Aurora-A, in addition to Aurora-...

Spiewak(Radoslaw),Stojek(Nimfa) Ann Agric Environ Med 2004-02-19

Rural inhabitants are exposed to considerable amounts of pesticides from water, soil and air. There are indications that...

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