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Partially functional Cenpa-GFP fusion protein causes increased chromosome misse…

Kalitsis(Paul),Fowler(Kerry J),Earle(Elizabe… Chromosome Res 2004-03-11

CENP-A is an essential histone H3-like protein that localizes to the centromeric region of eukaryotic chromosomes. Heter...

Dynamic behavior of Nuf2-Hec1 complex that localizes to the centrosome and cent…

Hori(Tetsuya),Haraguchi(Tokuko),Hiraoka(Yasu… J Cell Sci 2004-05-19

Nuf2 and Hec1 are evolutionarily conserved centromere proteins. To clarify the functions of these proteins in vertebrate...

Does a GATA factor make the bed for centromeric nucleosomes?

Chen(Ee Sin),Yanagida(Mitsuhiro),Takahashi(K… Cell Cycle 2004-05-11

CENP-A is an evolutionarily conserved, centromere-specific histone H3 variant. It remains a great mystery how CENP-A is ...

A functional relationship between NuMA and kid is involved in both spindle orga…

Levesque(Aime A),Howard(Louisa),Gordon(Micha… Mol Biol Cell 2004-04-08

We examined spindle morphology and chromosome alignment in vertebrate cells after simultaneous perturbation of the chrom...

Mitosin/CENP-F is a conserved kinetochore protein subjected to cytoplasmic dyne…

Yang(Zhen Ye),Guo(Jing),Li(Ning),Qian(Min),W… Cell Res 2004-02-09

Mitosin/CENP-F is a human nuclear protein transiently associated with the outer kinetochore plate in M phase and is invo...

Molecular targets for tumour progression in gastrointestinal stromal tumours.

Koon(N),Schneider-Stock(R),Sarlomo-Rikala(M)… Gut 2004-02-27

The distinction between benign and malignant gastrointestinal stromal tumours (GISTs) is often unclear at the clinical a...

Farnesylated proteins as anticancer drug targets: from laboratory to the clinic.

Russo(Patrizia),Loprevite(Maura),Cesario(Alf… Curr Med Chem Anticancer Agen… 2004-10-19

The knowledge that Ras was readily prenylated by protein FTase and that the inhibition of this reaction has the ability ...

Bub1 is required for kinetochore localization of BubR1, Cenp-E, Cenp-F and Mad2…

Johnson(Victoria L),Scott(Maria I F),Holt(Sa… J Cell Sci 2004-12-10

During mitosis, the recruitment of spindle-checkpoint-associated proteins to the kinetochore occurs in a defined order. ...

Dynamics of centromere and kinetochore proteins; implications for checkpoint si…

Shah(Jagesh V),Botvinick(Elliot),Bonday(Zahi… Curr Biol 2004-09-02

The mitotic checkpoint prevents the onset of anaphase before all chromosomes are attached to spindle microtubules. The c...

In vitro modification of human centromere protein CENP-C fragments by small ubi…

Chung(Tung-Liang),Hsiao(He-Hsuan),Yeh(Yuh-Yi… J Biol Chem 2004-10-25

Protein sumoylation by small ubiquitin-like modifier (SUMO) proteins is an important post-translational regulatory modif...

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