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Low-level arsenite induced gene expression in HEK293 cells.

Zheng(Xing Hui),Watts(George S),Vaught(Skip)… Toxicology 2003-05-20

Chronic, low-level exposure to arsenic frequently results in skin, lung, bladder, and kidney cancer. Since arsenic is pr...

Increasing complexity of farnesyltransferase inhibitors activity: role in chrom…

Falugi(Carla),Trombino(Sonya),Granone(Pierlu… Curr Cancer Drug Targets 2003-10-09

Oncogenic Ras proteins have been seen as an important target for novel anticancer drugs. Due to the functional role of R...

Human CENP-I specifies localization of CENP-F, MAD1 and MAD2 to kinetochores an…

Liu(Song-Tao),Hittle(James C),Jablonski(Sand… Nat Cell Biol 2003-05-16

The kinetochore, a macromolecular complex located at the centromere of chromosomes, provides essential functions for acc...

CENP-B box is required for de novo centromere chromatin assembly on human alpho…

Ohzeki(Jun-ichirou),Nakano(Megumi),Okada(Ter… J Cell Biol 2003-01-23

Centromere protein (CENP) B boxes, recognition sequences of CENP-B, appear at regular intervals in human centromeric alp...

Human centromere chromatin protein hMis12, essential for equal segregation, is …

Goshima(Gohta),Kiyomitsu(Tomomi),Yoda(Kinya)… J Cell Biol 2003-02-10

Kinetochores are the chromosomal sites for spindle interaction and play a vital role for chromosome segregation. The com...

A cell cycle-regulated GATA factor promotes centromeric localization of CENP-A …

Chen(Ee Sin),Saitoh(Shigeaki),Yanagida(Mitsu… Mol Cell 2003-03-18

CENP-A, the centromere-specific histone H3 variant, plays a crucial role in organizing kinetochore chromatin for precise...

In vivo functional dissection of human inner kinetochore protein CENP-C.

Trazzi(Stefania),Bernardoni(Roberto),Diolait… J Struct Biol 2003-06-27

CENP-C is a fundamental component of the inner kinetochore plate and contributes to the formation of functional centrome...

Proteasome-dependent processing of nuclear proteins is correlated with their su…

Dino Rockel(Thomas),von Mikecz(Anna) J Struct Biol 2003-06-27

Although proteasomes are abundant in the nucleoplasm little is known of proteasome-dependent proteolysis within the nucl...

Molecular cloning and sequence analysis of hamster CENP-A cDNA.

Figueroa(Javier),Pendón(Carlos),Valdivia(Man… BMC Genomics 2003-10-31

The centromere is a specialized locus that mediates chromosome movement during mitosis and meiosis. This chromosomal dom...

Expression and behaviour of CENP-E at kinetochores during mouse spermatogenesis.

Parra(María T),Page(Jesús),Yen(Tim J),He(Dac… Chromosoma 2003-01-28

Centromere protein E (CENP-E) is a microtubule motor protein localised in the outer kinetochore plate and in the fibrous...

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