CENP-C is a fundamental component of the inner kinetochore plate and contributes to the formation of functional centrome...
Although proteasomes are abundant in the nucleoplasm little is known of proteasome-dependent proteolysis within the nucl...
An adult female patient with a history of miscarriages was found to be carrying a stable supernumerary chromosome. The p...
The characterization of autoantibody specificities in rheumatic diseases is important in both diagnostic and basic resea...
We show that Trichostatin A (TSA)-induced partial histone hyperacetylation causes a unidirectional shift in the position...
Aneuploidy is the hallmark of many human cancers. Recent work has strongly suggested that chromosome missegregation duri...
Human neocentromeres are fully functional centromeres that arise at previously noncentromeric regions of the genome. We ...
Present study addresses the issue whether cellular antigens recognised by antinuclear autoantibodies are driven by apopt...
The Ran GTPase is required for nuclear assembly, nuclear transport, spindle assembly, and mitotic regulation. While the ...
The mitotic checkpoint prevents advance to anaphase prior to successful attachment of every centromere/kinetochore to mi...
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