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In vivo functional dissection of human inner kinetochore protein CENP-C.

Trazzi(Stefania),Bernardoni(Roberto),Diolait… J Struct Biol 2003-06-27

CENP-C is a fundamental component of the inner kinetochore plate and contributes to the formation of functional centrome...

Proteasome-dependent processing of nuclear proteins is correlated with their su…

Dino Rockel(Thomas),von Mikecz(Anna) J Struct Biol 2003-06-27

Although proteasomes are abundant in the nucleoplasm little is known of proteasome-dependent proteolysis within the nucl...

Prenatal diagnosis of a karyotypically normal pregnancy in a mother with a supe…

Knegt(A C),Li(S),Engelen(J J M),Bijlsma(E K)… Prenat Diagn 2003-10-09

An adult female patient with a history of miscarriages was found to be carrying a stable supernumerary chromosome. The p...

Advances in B-cell epitope analysis of autoantigens in connective tissue diseas…

Mahler(M),Blüthner(M),Pollard(K M) Clin Immunol 2003-07-08

The characterization of autoantibody specificities in rheumatic diseases is important in both diagnostic and basic resea...

Centromeric chromatin pliability and memory at a human neocentromere.

Craig(Jeffrey M),Wong(Lee H),Lo(Anthony W I)… EMBO J 2003-07-14

We show that Trichostatin A (TSA)-induced partial histone hyperacetylation causes a unidirectional shift in the position...

Overexpression and mistargeting of centromere protein-A in human primary colore…

Tomonaga(Takeshi),Matsushita(Kazuyuki),Yamag… Cancer Res 2003-08-25

Aneuploidy is the hallmark of many human cancers. Recent work has strongly suggested that chromosome missegregation duri...

A rapid method of genomic array analysis of scaffold/matrix attachment regions …

Sumer(Huseyin),Craig(Jeffrey M),Sibson(Mandy… Genome Res 2003-10-06

Human neocentromeres are fully functional centromeres that arise at previously noncentromeric regions of the genome. We ...

Antinuclear antibodies recognize cellular autoantigens driven by apoptosis.

Ramírez-Sandoval(Roxana),Sánchez-Rodríguez(S… Joint Bone Spine 2003-10-27

Present study addresses the issue whether cellular antigens recognised by antinuclear autoantibodies are driven by apopt...

The Ran GTPase regulates kinetochore function.

Arnaoutov(Alexei),Dasso(Mary) Dev Cell 2003-09-02

The Ran GTPase is required for nuclear assembly, nuclear transport, spindle assembly, and mitotic regulation. While the ...

Activating and silencing the mitotic checkpoint through CENP-E-dependent activa…

Mao(Yinghui),Abrieu(Ariane),Cleveland(Don W) Cell 2003-08-13

The mitotic checkpoint prevents advance to anaphase prior to successful attachment of every centromere/kinetochore to mi...

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