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The CENP-A homolog CaCse4p in the pathogenic yeast Candida albicans is a centro…

Sanyal(Kaustuv),Carbon(John) Proc Natl Acad Sci U S A 2002-11-13

The gene encoding CaCse4p, a homolog of the evolutionarily conserved histone H3-like kinetochore protein CENP-A, has bee...

Unstable kinetochore-microtubule capture and chromosomal instability following …

Putkey(Frances R),Cramer(Thorsten),Morphew(M… Dev Cell 2002-11-13

A selective disruption of the mouse CENP-E gene was generated to test how this kinetochore-associated, kinesin-like prot...

Development of a CENP-A/CENP-B-specific immune response in a patient with syste…

Mahler(Michael),Mierau(Rudolf),Genth(Ekkehar… Arthritis Rheum 2002-08-05

Antibodies directed against an epitope motif on CENP-A have been shown to cross-react with mimotopes on other autoantige...

Recognition of Granzyme B-generated autoantigen fragments in scleroderma patien…

Schachna(Lionel),Wigley(Fredrick M),Morris(S… Arthritis Rheum 2002-08-05

...CENPs was also performed.,GB-cleaved autoantigens were immunoblotted by 16 of 19 IDL sera (84.2%) compared with 6 of 15 ...

Proteomic analysis of human metaphase chromosomes reveals topoisomerase II alph…

Morrison(Ciaran),Henzing(Alexander J),Jensen… Nucleic Acids Res 2002-12-23

The essential Aurora B kinase is a chromosomal passenger protein that is required for mitotic chromosome alignment and s...

Ctf3p, the Mis6 budding yeast homolog, interacts with Mcm22p and Mcm16p at the …

Measday(Vivien),Hailey(Dale W),Pot(Isabelle)… Genes Dev 2002-01-25

The budding yeast kinetochore is composed of an inner and outer protein complex, which binds to centromere (CEN) DNA and...

CENP-A is phosphorylated by Aurora B kinase and plays an unexpected role in com…

Zeitlin(S G),Shelby(R D),Sullivan(K F) J Cell Biol 2002-01-30

Aurora B is a mitotic protein kinase that phosphorylates histone H3, behaves as a chromosomal passenger protein, and fun...

Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle…

Howell(B J),McEwen(B F),Canman(J C),Hoffman(… J Cell Biol 2002-01-30

We discovered that many proteins located in the kinetochore outer domain, but not the inner core, are depleted from kine...

CENP-C binds the alpha-satellite DNA in vivo at specific centromere domains.

Politi(Valeria),Perini(Giovanni),Trazzi(Stef… J Cell Sci 2002-12-03

CENP-C is a fundamental component of the centromere, highly conserved among species and necessary for the proper assembl...

Molecular behavior in living mitotic cells of human centromere heterochromatin …

Sugimoto(K),Tasaka(H),Dotsu(M) Cell Struct Funct 2002-10-08

We constructed stable mammalian cell lines in which human heterochromatin protein HP1alpha and kinetochore protein CENP-...

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