The generation in vitro of mammalian artificial chromosomes, in view of the possibility of developing new technologies f...
Autoimmune diseases arise from a host's immune response against self-antigens. The triggering events ultimately resultin...
53BP1 is a vertebrate BRCT motif protein, originally described as a direct interactor of p53, which has recently been sh...
All eukaryotes contain centromere-specific histone H3 variants (CenH3s), which replace H3 in centromeric chromatin. We h...
Human centromere protein C (CENP-C) is an essential component of the inner kinetochore plate. A central region of CENP-C...
A selective disruption of the mouse CENP-E gene was generated to test how this kinetochore-associated, kinesin-like prot...
The gene encoding CaCse4p, a homolog of the evolutionarily conserved histone H3-like kinetochore protein CENP-A, has bee...
Mice heterozygous for Robertsonian centric fusion chromosomal translocations frequently produce aneuploid sperm. In this...
Centromere protein B (CENP-B) is a constitutive protein that binds to a highly conserved 17bp motif located at most mamm...
We have reconstructed the evolution of the anciently derived kinesin superfamily using various alignment and tree-buildi...
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