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Insertion of a loxP site in a size-reduced human accessory chromosome.

Moralli(D),Vagnarelli(P),Bensi(M),De Carli(L… Cytogenet Cell Genet 2002-04-16

The generation in vitro of mammalian artificial chromosomes, in view of the possibility of developing new technologies f...

A population of autoantibodies against a centromere-associated protein A major …

Mahler(M),Mierau(R),Schlumberger(W),Blüthner… J Mol Med (Berl) 2002-04-25

Autoimmune diseases arise from a host's immune response against self-antigens. The triggering events ultimately resultin...

Kinetochore localisation of the DNA damage response component 53BP1 during mito…

Jullien(Denis),Vagnarelli(Paola),Earnshaw(Wi… J Cell Sci 2002-04-30

53BP1 is a vertebrate BRCT motif protein, originally described as a direct interactor of p53, which has recently been sh...

Recurrent evolution of DNA-binding motifs in the Drosophila centromeric histone.

Malik(Harmit S),Vermaak(Danielle),Henikoff(S… Proc Natl Acad Sci U S A 2002-03-07

All eukaryotes contain centromere-specific histone H3 variants (CenH3s), which replace H3 in centromeric chromatin. We h...

Mutational analysis of the central centromere targeting domain of human centrom…

Song(Kang),Gronemeyer(Bobbi),Lu(Wei),Eugster… Exp Cell Res 2002-05-20

Human centromere protein C (CENP-C) is an essential component of the inner kinetochore plate. A central region of CENP-C...

Unstable kinetochore-microtubule capture and chromosomal instability following …

Putkey(Frances R),Cramer(Thorsten),Morphew(M… Dev Cell 2002-11-13

A selective disruption of the mouse CENP-E gene was generated to test how this kinetochore-associated, kinesin-like prot...

The CENP-A homolog CaCse4p in the pathogenic yeast Candida albicans is a centro…

Sanyal(Kaustuv),Carbon(John) Proc Natl Acad Sci U S A 2002-11-13

The gene encoding CaCse4p, a homolog of the evolutionarily conserved histone H3-like kinetochore protein CENP-A, has bee...

Evidence for meiotic spindle checkpoint from analysis of spermatocytes from Rob…

Eaker(S),Pyle(A),Cobb(J),Handel(M A) J Cell Sci 2002-02-06

Mice heterozygous for Robertsonian centric fusion chromosomal translocations frequently produce aneuploid sperm. In this...

CENP-B is not critical for meiotic chromosome segregation in male mice.

Tomascik-Cheeseman(Lisa),Marchetti(Francesco… Mutat Res 2002-02-07

Centromere protein B (CENP-B) is a constitutive protein that binds to a highly conserved 17bp motif located at most mamm...

Maximum likelihood methods reveal conservation of function among closely relate…

Lawrence(Carolyn J),Malmberg(Russell L),Musz… J Mol Evol 2002-08-15

We have reconstructed the evolution of the anciently derived kinesin superfamily using various alignment and tree-buildi...

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