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DNA Instability Maintains the Repeat Length of the Yeast RNA Polymerase II C-te…

Morrill(Summer A),Exner(Alexandra E),Babokho… J Biol Chem 0000-00-00

...RAD52 is necessary for CTD repeat expansion but not contraction, identifying a role for recombination in repeat expansio...

PCNA SUMOylation protects against PCNA polyubiquitination-mediated, Rad59-depen…

Halas(Agnieszka),Krawczyk(Michal),Sledziewsk… Mutat Res 0000-00-00

...Rad52/Rad51/Rad59-dependent gene conversion. A 5- to 10-fold increase in the frequency of such recombination events is o...

Structure of the human DNA-repair protein RAD52 containing surface mutations.

Saotome(Mika),Saito(Kengo),Onodera(Keiichi),… Acta Crystallogr F Struct Bio… 0000-00-00

...RAD52 protein (RAD52(1-212)) forms an undecameric ring structure with a surface that is mostly positively charged. In th...

Characterization of a Novel MMS-Sensitive Allele of Schizosaccharomyces pombe m…

Ranatunga(Nimna S),Forsburg(Susan L) G3 (Bethesda) 0000-00-00

...Rad52, and require the damage checkpoint for viability, indicating genome stress. The mcm4-c106 mutant is synthetically ...

Multiple Rad52-Mediated Homology-Directed Repair Mechanisms Are Required to Pre…

Claussin(Clémence),Chang(Michael) PLoS Genet 0000-00-00

...Rad52 is required for almost all HDR mechanisms, and telomerase-null cells senesce faster in the absence of Rad52. Howev...

Biochemical characterization of plant Rad52 protein from rice (Oryza sativa).

Nair(Anuradha),Agarwal(Rachna),Chittela(Raja… Plant Physiol Biochem 0000-00-00

...RAD52 is absent in plant systems until lately. However, recent genetic studies have shown the presence of RAD52 homologu...

Zoledronic acid is an effective radiosensitizer in the treatment of osteosarcom…

Kim(Eun Ho),Kim(Mi-Sook),Lee(Kyung-Hee),Koh(… Oncotarget 0000-00-00

...Rad52, and DNA-PKcs), and decreased phosphorylation of PI3K-Akt and MAPK pathway proteins (Raf1, MEK1/2, ERK1/2, and Akt...

Genetic controls of DNA damage avoidance in response to acetaldehyde in fission…

Noguchi(Chiaki),Grothusen(Grant),Anandarajan… Cell Cycle 0000-00-00

...Rad52-DNA repair foci, while Atd2 and Atd3 have minor roles in acetaldehyde detoxification. We found that acetaldehyde c...

Small-molecule inhibitors identify the RAD52-ssDNA interaction as critical for …

Hengel(Sarah R),Malacaria(Eva),Folly da Silv… Elife 0000-00-00

...RAD52 is an emerging therapeutic target of high importance for BRCA-deficient tumors. Depletion of RAD52 is syntheticall...

DNA annealing by Redβ is insufficient for homologous recombination and the addi…

Subramaniam(Sivaraman),Erler(Axel),Fu(Jun),K… Sci Rep 0000-00-00

...RAD52 SSAPs share ancestral and mechanistic roots.

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