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TP53 BRCA1 CRISPR single-cell cancer

Cox(A D) Drugs 2001-10-11

New targets for drug discovery have been identified rapidly as a result of the many recent and rapid advances in the und...

Lo(A W),Magliano(D J),Sibson(M C),Kalitsis(P… Genome Res 2001-06-21

Centromere protein A (CENP-A) is an essential histone H3-related protein that constitutes the specialized chromatin of a...

Irelan(J T),Gutkin(G I),Clarke(L) Genetics 2001-06-07

Several members of protein families that are conserved in higher eukaryotes are known to play a role in centromere funct...

Sullivan(K F) Curr Opin Genet Dev 2001-05-17

Centromeres provide a distinctive mechanical function for the chromosomes as the site of kinetochore assembly and force ...

Van Hooser(A A),Ouspenski(I I),Gregson(H C),… J Cell Sci 2001-12-31

The mechanisms that specify precisely where mammalian kinetochores form within arrays of centromeric heterochromatin rem...

Blajeski(A L),Kottke(T J),Kaufmann(S H) Exp Cell Res 2001-12-07

Despite extensive previous investigation, the events occurring between paclitaxel-induced mitotic arrest and the subsequ...

Fukagawa(T),Regnier(V),Ikemura(T) Nucleic Acids Res 2001-10-11

CENP-C is an evolutionarily conserved centromere protein that is thought to be an important component in kinetochore ass...

McEwen(B F),Chan(G K),Zubrowski(B),Savoian(M… Mol Biol Cell 2001-12-04

CENP-E is a kinesin-like protein that when depleted from mammalian kinetochores leads to mitotic arrest with a mixture o...

Dol'nik(A V),Luk'ianov(D V),Enukashvili(N I)… Tsitologiia 2001-10-25

Immunoblot revealed in spermatozoa alpha-satellite (sat) DNA-specific centromere protein B (CENP-B) and p70 (Enukashvily...

Kobayashi(M),Hanai(R) Biochem Biophys Res Commun 2001-10-04

Two isoforms, 1 and 2, of human DNA topoisomerase IIIbeta were expressed in HeLa cells as a fusion protein to the C-term...

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