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Salinas-Luypaert(C),Dubocanin(D),Lee(RJ),A... Nat Genet 2025-10-00

Maintaining the epigenetic identity of centromeres is essential to prevent genome instability. Centromeres are epigeneti...

Pettkó-Szandtner(A),Magyar(Z),Komaki(S) Plant Physiol 2025-09-30

The kinetochore, critical for accurate chromosome segregation and genome stability in eukaryotes, comprises the Constitu...

He(R),Xu(Y),Zhang(P),Yu(L),Ma(J),Cui(Y) J Clin Transl Hepatol 2025-12-28

Cell cycle checkpoint-related genes (CCCRGs) are implicated in the development and progression of hepatocellular carcino...

Ostadian(C),Hayati(N),Zahiri Sorouri(Z),Ho... Int J Fertil Steril 2025-09-30

The success rate of in vitro maturation (IVM) for human oocytes is clinically significant, prompting a focus on optimizi...

Pukało(Z),Medina-Pritchard(B),Abad(MA),Jey... Chromosome Res 2025-09-30

Four decades ago, the discovery of centromere protein-A (CENP-A) marked a pivotal breakthrough in chromosome biology, re...

Birchak(GJ),Gibson(DG),Allu(PK),Kashyap(P)... bioRxiv 2025-10-03

The ongoing development of human artificial chromosomes (HACs) will permit investigation into essential centromere proce...

Saito(M),Okumura(K),Tokunaga(Y),Tanaka(S),... Cancer Sci 2025-12-00

CENP-C, an essential component of the kinetochore, connects centromeric chromatin to the outer kinetochore, and thereby ...

Tullius(TW),Heuer(RA),Bohaczuk(SC),Mallory... bioRxiv 2025-10-05

The transmission of the paternal genome requires extensive chromatin reorganization, in which nucleosomes are largely re...

Laffitte(A),Lin(D),Tian(YJ),Liu(N),Lusk(CP... bioRxiv 2025-10-09

While homologous recombination (HR) is often considered to be an error-free DNA repair mechanism, the fidelity of this p...

Taneja(N),Chauhan(A),Mehra(V),Singh(S) Gene 2025-10-10

Holliday Junction Recognition Protein (HJURP) is essential for centromere integrity and chromosomal stability through it...