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[Interaction between checkpoint genes RAD9, RAD17, RAD24, and RAD53 involved in…

Koltovaia(N A),Nikulushkina(Iu V),Poshchina(… Genetika 2008-09-30

...RAD17, RAD24, and RAD53 in cell radioresistance, double mutants were analyzed for cell sensitivity to ionizing radiation...

Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effec…

Salvati(Erica),Leonetti(Carlo),Rizzo(Angela)… J Clin Invest 2008-04-02

...RAD17, and 53BP1. This was dependent on DNA repair enzyme ATR, correlated with delocalization of the protective telomeri...

Roles of Saccharomyces cerevisiae RAD17 and CHK1 checkpoint genes in the repair…

Bracesco(Nelson),Candreva(Ema C),Keszenman(D… Radiat Environ Biophys 2008-02-06

...rad17Delta/rad17Delta, and an isogenic wild-type strain were exposed to the radiomimetic agent bleomycin (BLM). DNA doub...

Loss of CHK1 function impedes DNA damage-induced FANCD2 monoubiquitination but …

Guervilly(Jean-Hugues),Macé-Aimé(Gaëtane),Ro… Hum Mol Genet 2008-03-14

...RAD17 are required for DNA interstrand cross-link (ICL) resistance and for the optimal activation of FANCD2. Moreover, w...

Downregulation of RAD17 in head and neck cancer.

Zhao(Ming),Begum(Shahnaz),Ha(Patrick K),West… Head Neck 2008-03-28

...RAD17 protein in primary tumor tissue (0/12), while there was strong expression of hRAD17 protein in normal oral mucosal...

DNA repair by polymerase delta in Saccharomyces cerevisiae is not controlled by…

Cardone(J M),Brendel(M),Henriques(J A P) Genet Mol Res 2008-03-18

...Rad17, Mec3 and Ddc1 subunits is an early response factor to DNA damage and activates checkpoints. This complex is struc...

Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response.

Morin(Isabelle),Ngo(Hien-Ping),Greenall(Aman… EMBO J 2008-10-23

...Rad17, Rad9, Rad53 and Mec1, but is largely independent of Chk1, Tel1 and Dun1. Serines S372, S567, S587 and S692 of Exo...

The Caenorhabditis elegans Rad17 homolog HPR-17 is required for telomere replic…

Boerckel(Julie),Walker(Dana),Ahmed(Shawn) Genetics 2007-09-13

...Rad17 RFC clamp loader homolog, hpr-17, functions in the same pathway as the 9-1-1 complex with regard to both the DNA d...

Clamping the Mec1/ATR checkpoint kinase into action.

Majka(Jerzy),Burgers(Peter M J) Cell Cycle 2007-12-13

...Rad17-Mec3-Ddc1 (human 9-1-1) is loaded onto gapped DNA resulting from the partial repair of DNA damage, and the Ddc1 su...

Phosphorylation of histone H2AX in radiation-induced micronuclei.

Medvedeva(Natalia G),Panyutin(Irina V),Panyu… Radiat Res 2007-10-30

...Rad17, that co-localized with gamma-H2AX foci in the main nuclei were not found in the micronuclei. Combination of the m...

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