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Replication of the 2,6-diamino-4-hydroxy-N(5)-(methyl)-formamidopyrimidine (MeF…

Christov(Plamen P),Yamanaka(Kinrin),Choi(Jeo… Chem Res Toxicol 2012-12-26

...Rev1, ν, and yPol ζ) polymerases to address its miscoding potential. The MeFapy-dGuo was found to be a strong block to t...

Regulation of Rev1 by the Fanconi anemia core complex.

Kim(Hyungjin),Yang(Kailin),Dejsuphong(Donnip… Nat Struct Mol Biol 2012-03-21

...Rev1. FAAP20 binding stabilizes Rev1 nuclear foci and promotes interaction of the Fanconi anemia core with PCNA-Rev1 DNA...

The vital role of polymerase ζ and REV1 in mutagenic, but not correct, DNA synt…

Hashimoto(Keiji),Cho(Youngjin),Yang(In-Young… J Biol Chem 2012-06-12

...REV1 cDNA into Rev1(-/-) MEFs restored the mutagenic TLS, but a REV1 mutant lacking the C terminus did not. Yeast and ma...

Kinetic analysis of the bypass of a bulky DNA lesion catalyzed by human Y-famil…

Sherrer(Shanen M),Sanman(Laura E),Xia(Cynthi… Chem Res Toxicol 2012-07-03

...Rev1 (hRev1). Our running start assays demonstrated that each of these enzymes was indeed capable of traversing a site-s...

The C-terminal domain of human Rev1 contains independent binding sites for DNA …

Pustovalova(Yulia),Bezsonova(Irina),Korzhnev… FEBS Lett 2012-12-05

Human Rev1 is a translesion synthesis (TLS) DNA polymerase involved in bypass replication across sites of DNA damage and...

Repair of cisplatin-induced DNA interstrand crosslinks by a replication-indepen…

Enoiu(Milica),Jiricny(Josef),Schärer(Orlando… Nucleic Acids Res 2012-12-28

...Rev1 and Polζ are involved in the error-free bypass of cisplatin ICLs. The requirement for CSB, Rev1 or Polζ is specific...

Structural basis of Rev1-mediated assembly of a quaternary vertebrate translesi…

Wojtaszek(Jessica),Lee(Chul-Jin),D'Souza(San… J Biol Chem 2012-12-14

...Rev1 CTD provides the first molecular explanation of the essential scaffolding function of Rev1 and highlights the Rev1 ...

Structural basis of recruitment of DNA polymerase ζ by interaction between REV1…

Kikuchi(Sotaro),Hara(Kodai),Shimizu(Toshiyuk… J Biol Chem 2012-12-14

...REV1, REV7, and a REV3 fragment. The REV1 C-terminal domain adopts a four-helix bundle that interacts with REV7. A linke...

Characterization of outer membrane vesicles from Brucella melitensis and protec…

Avila-Calderón(Eric Daniel),Lopez-Merino(Ahi… Clin Dev Immunol 2012-05-07

...Rev1 (P < 0.005). Additionally, the levels of serum IgG2a increased in mice vaccinated with OMVs from rough strain VTRM1...

Stalled Polη at its cognate substrate initiates an alternative translesion synt…

Ito(Wakana),Yokoi(Masayuki),Sakayoshi(Nobuta… Genes Cells 2012-12-06

...REV1, and REV1 interacts with other TLS polymerases including Polι, Polκ and Polζ, Polη may play a role in recruitment o...

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