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Protamine lacunae preserve the paternal chromatin landscape in sperm.

Tullius(TW),Heuer(RA),Bohaczuk(SC),Mallory... bioRxiv 2025-10-05

The transmission of the paternal genome requires extensive chromatin reorganization, in which nucleosomes are largely re...

Tumor suppressor roles of CENP-E and Nsl1 in Drosophila epithelial tissues.

Clemente-Ruiz(Marta),Muzzopappa(Mariana),M... Cell Cycle 2016-04-28

Depletion of spindle assembly checkpoint (SAC) genes in Drosophila epithelial tissues leads to JNK-dependent programmed ...

Acquired resistance to metformin in breast cancer cells triggers transcriptom...

Oliveras-Ferraros(Cristina),Vazquez-Martin... Cell Cycle 2016-05-09

Therapeutic interventions based on metabolic inhibitor-based therapies are expected to be less prone to acquired resista...

CRL4(RBBP7) is required for efficient CENP-A deposition at centromeres.

Mouysset(Julien),Gilberto(Samuel),Meier(Mi... J Cell Sci 2016-02-08

The mitotic spindle drives chromosome movement during mitosis and attaches to chromosomes at dedicated genomic loci name...

Preventing farnesylation of the dynein adaptor Spindly contributes to the mit...

Holland(Andrew J),Reis(Rita M),Niessen(She... Mol Biol Cell 2016-02-09

The clinical interest in farnesyltransferase inhibitors (FTIs) makes it important to understand how these compounds affe...

Quinoline-based clioquinol and nitroxoline exhibit anticancer activity induci...

Chan-On(Waraporn),Huyen(Nguyen Thi Bich),S... Drug Des Devel Ther 2016-09-13

Fork head box M1 (FoxM1) is an oncogenic transcription factor frequently elevated in numerous cancers, including cholang...

Second generation analysis of antinuclear antibody (ANA) by combination of sc...

Scholz(Juliane),Grossmann(Kai),Knütter(Ilk... Clin Chem Lab Med 2016-09-09

For the serological diagnosis of systemic autoimmune rheumatic diseases, a two-tier approach starting with sensitive ant...

Aneuploidy generates proteotoxic stress and DNA damage concurrently with p53-...

Ohashi(Akihiro),Ohori(Momoko),Iwai(Kenichi... Nat Commun 2016-04-18

The molecular mechanism responsible that determines cell fate after mitotic slippage is unclear. Here we investigate the...

Epigenetic Regulation of Chromatin States in Schizosaccharomyces pombe.

Allshire(Robin C),Ekwall(Karl) Cold Spring Harb Perspect Biol 2016-04-13

This article discusses the advances made in epigenetic research using the model organism fission yeast Schizosaccharomyc...

Defining the catalytic activity of nanoceria in the P23H-1 rat, a photorecept...

Wong(Lily L),Pye(Quentin N),Chen(Lijuan),S... PLoS One 2016-04-18

...CeNPs injection compared to saline. Additionally, reduction of lipid peroxidation in the retinas of CeNPs-treated vs sal...

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