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Defective DNA repair and chromatin organization in patients with quiescent syst…

Souliotis(Vassilis L),Vougas(Konstantinos),G… Arthritis Res Ther 0000-00-00

...RAD50, PARP1, MLH1, MLH3, and ATM were significantly underexpressed in SLE versus controls, whereas PPP1R15A, BARD1 and ...

RINT-1 interacts with MSP58 within nucleoli and plays a role in ribosomal gene …

Yang(Chuan-Pin),Kuo(Yu-Liang),Lee(Yi-Chao),L… Biochem Biophys Res Commun 0000-00-00

...Rad50-interacting protein 1 (RINT-1), as a MSP58-binding protein. RINT-1 was implicated in the cell cycle checkpoint, me...

Bisphenol A-Induced Ovotoxicity Involves DNA Damage Induction to Which the Ovar…

Ganesan(Shanthi),Keating(Aileen F) Toxicol Sci 0000-00-00

...Rad50, and Smc1a) were increased (P < .05) after 1 day of BPA exposure. mRNA encoding Meh, Gstm, c-kit, Kitlg, and Akt w...

Mdc1 modulates the interaction between TopBP1 and the MRN complex during DNA da…

Choi(Seung Ho),Yoo(Hae Yong) Biochem Biophys Res Commun 0000-00-00

...Rad50-Nbs1 (MRN) complex in egg extracts in a checkpoint-regulated manner. In this study, we show that Mdc1 associates w...

Reevaluation of RINT1 as a breast cancer predisposition gene.

Li(Na),Thompson(Ella R),Rowley(Simone M),McI… Breast Cancer Res Treat 0000-00-00

Rad50 interactor 1 (RINT1) has recently been reported as an intermediate-penetrance (odds ratio 3.24) breast cancer susc...

MRNIP/C5orf45 Interacts with the MRN Complex and Contributes to the DNA Damage …

Staples(Christopher J),Barone(Giancarlo),Mye… Cell Rep 0000-00-00

...RAD50-NBS1 (MRN) damage-sensing complex. Hence, we rename C5orf45 as MRNIP for MRN-interacting protein (MRNIP). We find ...

A network of allosterically coupled residues in the bacteriophage T4 Mre11-Rad5…

Gao(Yang),Meyer(Jennifer R),Nelson(Scott W) Protein Sci 0000-00-00

The Mre11-Rad50 (MR) protein complex, made up of a nuclease and ATPase, respectively, is involved in the processing of d...

Increased DNA double-strand break was associated with downregulation of repair …

Suman(Shubhankar),Kumar(Santosh),N&#x27;Gouemo(Pr… Alcohol 0000-00-00

...Rad50, and Ku86 as well as increased Bax and p21 in samples from ethanol-treated rats. Additionally, we also observed in...

RINT1 functions as a multitasking protein at the crossroads between genomic sta…

Grigaravicius(Paulius),von Deimling(Andreas)… Autophagy 0000-00-00

...RAD50-interacting protein and its function was therefore linked to the maintenance of genomic stability. It was also sho...

Women at high risk of breast cancer: Molecular characteristics, clinical presen…

Kleibl(Zdenek),Kristensen(Vessela N) Breast 0000-00-00

...RAD50, NBS1, BRIP1, FANCA, FANCC, FANCM, RAD51, RAD51B, RAD51C, RAD51D, and XRCC2 have been described as high- or modera...

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