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The Saccharomyces cerevisiae Mre11-Rad50-Xrs2 complex promotes trinucleotide re…

Ye(Yanfang),Kirkham-McCarthy(Lucy),Lahue(Rob… DNA Repair (Amst) 0000-00-00

...Rad50. Mutation of all six lysine residues to arginine gave partial bypass of a sin3 HDAC mutant, suggesting that Rad50 ...

The Rb binding domain of HPV31 E7 is required to maintain high levels of DNA re…

Johnson(Bryan A),Aloor(Heather L),Moody(Cary… Virology 0000-00-00

...Rad50, and NBS1, as well as the homologous recombination repair proteins BRCA1 and Rad51. Interestingly, we have found t...

[Mutant Rad50 enhances killing effects of radiation on nasopharyngeal carcinoma…

Yan(R C),Wang(J),Huang(Z Z),Wang(Z Y),Wu(X F… Zhonghua Er Bi Yan Hou Tou Ji… 0000-00-00

...Rad50-GFP carrying mutant Rad50 gene. The expressions of Mre11, Rad50, Nbs1, and relevant constituents composing MRN com...

DNA damage precedes apoptosis during the regression of the interdigital tissue …

Montero(Juan A),Sanchez-Fernandez(Cristina),… Sci Rep 0000-00-00

...Rad50 and 53BP1 suggests a defensive response of cells against DNA damage. The relative distribution of cells γH2AX-only...

Frequency of pathogenic germline mutation in CHEK2, PALB2, MRE11, and RAD50 in …

Kim(Haeyoung),Cho(Dae-Yeon),Choi(Doo Ho),Oh(… Breast Cancer Res Treat 0000-00-00

...RAD50 c.1276C>T, and RAD50 c.3811_3813delGAA were newly identified in this study. A total of 15 missense variants were f...

Whole-exome sequencing of Finnish hereditary breast cancer families.

Määttä(Kirsi),Rantapero(Tommi),Lindström(Ann… Eur J Hum Genet 0000-00-00

...RAD50 was detected in a male BC patient. In addition, a very rare BRCA1 variant was identified in a single high-risk fam...

High Expression of MRE11-RAD50-NBS1 Is Associated with Poor Prognosis and Chemo…

Altan(Bolag),Yokobori(Takehiko),Ide(Munenori… Anticancer Res 0000-00-00

...Rad50 (RAD50) and Nijmegen breakage syndrome 1 (NBS1) proteins coordinate the detection and repair of DNA double-strand ...

Panel of SEREX-defined antigens for breast cancer autoantibodies profile detect…

Kostianets(Olga),Shyyan(Maksym),Antoniuk(Ste… Biomarkers 0000-00-00

...RAD50, PARD3, SPP1, SAP30BP, NY-BR-62 and NY-CO-58) was identified, which can differentiate breast cancer patients and h...

BATF Modulates the Th2 Locus Control Region and Regulates CD4+ T Cell Fate duri…

Bao(Katherine),Carr(Tiffany),Wu(Jianxuan),Ba… J Immunol 0000-00-00

...Rad50 hypersensitivity site (RHS)6 and RHS7 of the locus control region relative to AP-1 sites surrounding type-2 cytoki...

Xrs2 Dependent and Independent Functions of the Mre11-Rad50 Complex.

Oh(Julyun),Al-Zain(Amr),Cannavo(Elda),Cejka(… Mol Cell 0000-00-00

...Rad50-Xrs2/Nbs1 (MRX/N) complex orchestrates the cellular response to DSBs through its structural, enzymatic, and signal...

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