The amyloid precursor protein (APP) and its homologs amyloid precursor-like protein 1 (APLP1) and APLP2 have central phy...
...APLP2. We previously documented that APLP2-/-APLP1-/- and APLP2-/-APP-/- mice die postnatally, while APLP1-/-APP-/- mice...
...APLP2. Omission of the latter exons in L-APP and L-APLP2 isoforms, respectively, generates a functional recognition sequ...
...APLP2 (APLPs), are processed in a very similar manner by the same protease activities. A putative candidate involved in ...
...APLP2 have a similar physiological function (9). In contrast, APLP1 is believed to differ functionally from APP and APLP...
...APLP2) knock-out background showed that mutation of Tyr(682) results in postnatal lethality and neuromuscular synapse de...
...APLP2 mRNAs had previously been quantified in these samples (Johnston et al. (1996) Mol. Brain Res., in press) and subje...
...APLP2). The neurotoxic amyloid beta-peptide (Abeta) originates from APP, which is the only member of this protein family...
...APLP2), during cutaneous wound repair using a full-thickness excisional wound healing model in mice. In unwounded skin A...
...APLP2) mice present postnatal lethality and neuromuscular synapse defects. Previous work has shown that the APP intracel...
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