Literature Search

Kim(Tae-Won),Kim(Young-Jung),Kim(Hyun-Tae),P… Pharmacol Rep 2016-09-29

...Rad50-Nbs1 (MRN) complex, a DNA double-strand breaks (DSBs) sensor, in the development of nephrotoxicity following cispl...

Wang(Mo-Jin),Ping(Jie),Li(Yuan),Holmqvist(An… Medicine (Baltimore) 2016-05-04

...RAD50 (HR 0.348, 95% CI, 0.106-1.192; P = 0.026) were significantly associated with poor CSS of colorectal MC patients. ...

Lavin(Martin F),Kozlov(Sergei),Gatei(Magtouf… Biomolecules 2016-06-17

...Rad50/Nbs1 (MRN complex) play key roles in this process. The MRN complex rapidly recognises and locates to DNA DSB where...

De Falco(Mariarosaria),Catalano(Federico),Ro… PLoS One 2016-06-16

...RAD50 proteins to facilitate efficient DNA double-strand break end processing during homologous recombinational repair. ...

Balestrini(Alessia),Nicolas(Laura),Yang-Lott… Mol Cancer Res 2016-10-31

...Rad50, and Nbs1) occupies a central node of the DNA damage response (DDR) network and is required for ATM activation in ...

Pennisi(Rosa),Ascenzi(Paolo),di Masi(Alessan… Biomolecules 2016-07-13

...RAD50/NBN complex, have been described to be client proteins of Hsp90, which acts as a regulator of the diverse DDR path...

Chen(J),Zhang(J),Hu(H),Jin(Y),Xue(M) Tissue Antigens 2016-09-22

...RAD50 (rs6871536) and IL1RL1 (rs1558641) are associated with the development of atopic asthma in Chinese population. Gen...

Zhang(Min),Liu(Guoyan),Xue(Fengxia),Edwards(… Gynecol Oncol 2016-08-16

...RAD50 deletion is a marker of BRCAness. The RAD50 deletion occurred in 18% of BRCAwt OvCa patients. RAD50 deletion led t...

Frimer(Marina),Levano(Kelly S),Rodriguez-Gab… Gynecol Oncol 2016-08-16

...RAD50, NBN, ATM). Patients with HER2 overexpression (2/7, 28.6%) had germline HR mutations and were platinum-sensitive. ...

Iwasaki(Daichi),Hayashihara(Kayoko),Shima(Hi… PLoS Genet 2016-08-03

...Rad50-Xrs2/Nbs1 (MRX/N) complex, and its function is critical for the primary step of DSB repair, whether by homologous ...