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Structural basis of Rev1-mediated assembly of a quaternary vertebrate translesi…

Wojtaszek(Jessica),Lee(Chul-Jin),D'Souza(San… J Biol Chem 2012-12-14

...Rev1 CTD provides the first molecular explanation of the essential scaffolding function of Rev1 and highlights the Rev1 ...

Structural basis of recruitment of DNA polymerase ζ by interaction between REV1…

Kikuchi(Sotaro),Hara(Kodai),Shimizu(Toshiyuk… J Biol Chem 2012-12-14

...REV1, REV7, and a REV3 fragment. The REV1 C-terminal domain adopts a four-helix bundle that interacts with REV7. A linke...

Crystallization and X-ray diffraction analysis of the ternary complex of the C-…

Kikuchi(Sotaro),Hara(Kodai),Shimizu(Toshiyuk… Acta Crystallogr Sect F Struc… 2012-11-05

REV1, REV3 and REV7 are pivotal proteins in translesion DNA synthesis that allows DNA synthesis to continue even in the ...

Genetic variation in genes encoding for polymerase ζ subunits associates with b…

Varadi(Verena),Bevier(Melanie),Grzybowska(Ew… Breast Cancer Res Treat 2012-09-14

...REV1) because of their previously reported association with chromosomal instability and/or tumorigenesis. We selected po...

polo Is Identified as a Suppressor of bubR1 Nondisjunction in a Deficiency Scre…

Sousa-Guimarães(Sofia),Sunkel(Claudio),Malma… G3 (Bethesda) 2012-09-10

...rev1) meiotic phenotypes. We tested 65 deficiencies covering 60% of the third chromosome euchromatin. Among them, we cha...

Competition between replicative and translesion polymerases during homologous r…

Kane(Daniel P),Shusterman(Michael),Rong(Yika… PLoS Genet 2012-09-26

...Rev1, which interacts with multiple translesion polymerases, results in increased synthesis during gap repair. Together,...

Temporally distinct translesion synthesis pathways for ultraviolet light-induce…

Temviriyanukul(Piya),van Hees-Stuivenberg(Sa… DNA Repair (Amst) 2012-09-28

...Rev1 and the B family TLS Polζ in TLS and in the suppression of DNA damage signaling and genome instability after exposu...

Analysis of mice deficient in both REV1 catalytic activity and POLH reveals an …

Kano(Chie),Hanaoka(Fumio),Wang(Ji-Yang) Int Immunol 2012-06-11

...REV1 (REV1AA) exhibit reduction of both C to G and G to C transversions and moderate decrease of A/T mutations, whereas ...

Synthetic lethal targeting of DNA double-strand break repair deficient cells by…

Sultana(Rebeka),McNeill(Daniel R),Abbotts(Ra… Int J Cancer 2012-12-10

...Rev1)]. ii) Human cancer cells: BRCA1 deficient (MDA-MB-436), BRCA1 proficient (MCF-7), BRCA2 deficient (CAPAN-1 and HeL...

Multifaceted recognition of vertebrate Rev1 by translesion polymerases ζ and κ.

Wojtaszek(Jessica),Liu(Jiangxin),D'Souza(San… J Biol Chem 2012-10-11

...Rev1 CTD. Binding of the mouse Pol κ RIR to the Rev1 CTD induces folding of the disordered RIR peptide into a three-turn...

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