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Cenp-E inhibitor GSK923295: Novel synthetic route and use as a tool to genera...

Bennett(Ailsa),Bechi(Beatrice),Tighe(Antho... Oncotarget 2016-06-13

Aneuploidy is a common feature of cancer, with human solid tumour cells typically harbouring abnormal chromosome complem...

Point mutation impairs centromeric CENH3 loading and induces haploid plants.

Karimi-Ashtiyani(Raheleh),Ishii(Takayoshi)... Proc Natl Acad Sci U S A 2016-01-06

The chromosomal position of the centromere-specific histone H3 variant CENH3 (also called "CENP-A") is the assembly site...

Interpretation of an Extended Autoantibody Profile in a Well-Characterized Au...

Patterson(K A),Roberts-Thomson(P J),Lester... Arthritis Rheumatol 2016-03-14

To determine the relationships between systemic sclerosis (SSc)-related autoantibodies, as well as their clinical associ...

Defining the catalytic activity of nanoceria in the P23H-1 rat, a photorecept...

Wong(Lily L),Pye(Quentin N),Chen(Lijuan),S... PLoS One 2016-04-18

...CeNPs injection compared to saline. Additionally, reduction of lipid peroxidation in the retinas of CeNPs-treated vs sal...

HJURP involvement in de novo CenH3(CENP-A) and CENP-C recruitment.

Tachiwana(Hiroaki),Müller(Sebastian),Blüme... Cell Rep 2016-01-04

Although our understanding of centromere maintenance, marked by the histone H3 variant CenH3(CENP-A) in most eukaryotes,...

Chromokinesin Kid and kinetochore kinesin CENP-E differentially support chrom...

Iemura(Kenji),Tanaka(Kozo) Nat Commun 2016-02-18

Chromosome congression is the alignment of chromosomes at the spindle equator, and is a prerequisite for faithful chromo...

Mitotic Protein CSPP1 Interacts with CENP-H Protein to Coordinate Accurate Ch...

Zhu(Lijuan),Wang(Zhikai),Wang(Wenwen),Wang... J Biol Chem 2016-05-06

Mitotic chromosome segregation is orchestrated by the dynamic interaction of spindle microtubules with the kinetochores....

Anti-centromere protein A antibodies in systemic sclerosis: Significance and ...

Perosa(Federico),Prete(Marcella),Di Lernia... Autoimmun Rev 2016-05-16

Systemic sclerosis (SSc) is systemic, autoimmune, connective tissue disorder characterized by vascular abnormalities, co...

Identification of the centromeric repeat in the threespine stickleback fish (...

Cech(Jennifer N),Peichel(Catherine L) Chromosome Res 2016-09-15

Centromere sequences exist as gaps in many genome assemblies due to their repetitive nature. Here we take an unbiased ap...

High evolutionary turnover of satellite families in Caenorhabditis.

Subirana(Juan A),Albà(M Mar),Messeguer(Xav... BMC Evol Biol 2016-01-26

The high density of tandem repeat sequences (satellites) in nematode genomes and the availability of genome sequences fr...

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