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An Interleukin 13 Polymorphism Is Associated with Symptom Severity in Adult Sub…

Accordini(Simone),Calciano(Lucia),Bombieri(C… PLoS One 2016-08-03

...RAD50/IL13/IL4) was associated with STS (TG/GG vs TT genotype: uncorrected p-value = 0.00006, FDR-corrected p-value = 0....

[The preparation of recombinant adenovirus Ad-Rad50-GFP and detection of the op…

Yan(Ruicheng),Huang(Jiancong),Zhu(Ling),Chan… Lin Chung Er Bi Yan Hou Tou J… 2016-06-21

...Rad50-GFP carrying a mutant Rad50 gene expression region on the cell growth of nasopharyngeal carcinoma and the viral am...

Tel1 and Rif2 Regulate MRX Functions in End-Tethering and Repair of DNA Double-…

Cassani(Corinne),Gobbini(Elisa),Wang(Weibin)… PLoS Biol 2016-06-21

...Rad50-Xrs2 in yeast; Mre11-Rad50-Nbs1 in mammals), which recruits the checkpoint kinase Tel1/ATM to DSBs. In Saccharomyc...

DNA binding to SMC ATPases-trapped for release.

Schüler(Herwig),Sjögren(Camilla) EMBO J 2016-08-23

The SMC/Rad50/RecN proteins are universal DNA‐associated ABC‐type ATPases with crucial functions in genome maintenance. ...

Long non-coding RNAs as novel expression signatures modulate DNA damage and rep…

Zhou(Zhiheng),Liu(Haibai),Wang(Caixia),Lu(Qi… Sci Rep 2016-08-24

...RAD50, XRCC1 and BARD1). Cadmium increased ENST00000414355 expression in the lung of Cd-exposed rats in a dose-dependent...

RAD50 phosphorylation promotes ATR downstream signaling and DNA restart followi…

Gatei(Magtouf),Kijas(Amanda W),Biard(Denis),… Hum Mol Genet 2016-03-22

The MRE11/RAD50/NBN (MRN) complex plays a key role in detecting DNA double-strand breaks, recruiting and activating atax...

RADical response puts an exceptional responder in CHKmate: a synthetic lethal c…

Peng(Guang),Woodman(Scott E),Mills(Gordon B) Cancer Discov 2016-06-02

...RAD50 gene as a likely contributing factor to an unusual curative response to systemic combination therapy employing the...

Synthetic lethality in ATM-deficient RAD50-mutant tumors underlies outlier resp…

Al-Ahmadie(Hikmat),Iyer(Gopa),Hohl(Marcel),A… Cancer Discov 2016-06-02

...RAD50 that attenuated ATM signaling which in the context of CHK1 inhibition contributed, via synthetic lethality, to ext...

Gingival fibroblasts resist apoptosis in response to oxidative stress in a mode…

Cheng(R),Choudhury(D),Liu(C),Billet(S),Hu(T)… Cell Death Discov 2016-08-23

...Rad50. Detection of apoptosis-related proteins also showed anti-apoptotic effects and pro-apoptotic effects were balance...

BRCA1-CtIP interaction in the repair of DNA double-strand breaks.

Aparicio(Tomas),Gautier(Jean) Mol Cell Oncol 2016-09-21

...RAD50-NBS1 (MRN) nuclease complex cooperate with BRCA1 to specifically repair topoisomerase II-DNA adducted breaks. In c...

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