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DNA damage bypass operates in the S and G2 phases of the cell cycle and exhibit…

Diamant(Noam),Hendel(Ayal),Vered(Ilan),Carel… Nucleic Acids Res 2012-02-27

...Rev1. Analysis of TLS using a high-resolution gapped-plasmid assay system in cell populations enriched by centrifugal el...

PCNA ubiquitination is important, but not essential for translesion DNA synthes…

Hendel(Ayal),Krijger(Peter H L),Diamant(Noam… PLoS Genet 2012-01-23

...Rev1 in Pcna(K164R/K164R) mouse embryo fibroblasts caused each an increased sensitivity to UV radiation, indicating the ...

REV1 and polymerase ζ facilitate homologous recombination repair.

Sharma(Shilpy),Hicks(J Kevin),Chute(Colleen … Nucleic Acids Res 2012-03-14

...REV1 and Polζ-dependent DNA repair. Thus, the REV1/Polζ complex maintains genomic stability by directly participating in...

Different sets of translesion synthesis DNA polymerases protect from genome ins…

Temviriyanukul(Piya),Meijers(Matty),van Hees… Toxicol Sci 2012-08-08

...Rev1 as well as in Rev3, the catalytic subunit of TLS Polζ. After exposure, cellular survival, replication fork progress...

Crosstalk between replicative and translesional DNA polymerases: PDIP38 interac…

Tissier(Agnès),Janel-Bintz(Régine),Coulon(St… DNA Repair (Amst) 2011-01-03

...Rev1 and Polzeta (via Rev7). We thus suggest that PDIP38 serves as a mediator protein helping TLS Pols to transiently re...

Regulation of tolerance to DNA alkylating damage by Dot1 and Rad53 in Saccharom…

Conde(Francisco),Ontoso(David),Acosta(Isabel… DNA Repair (Amst) 2011-01-13

...Rev1 foci. We propose that threshold levels of Rad53 activity exquisitely modulate the tolerance to alkylating damage at...

Integrated ligand-receptor bioinformatic and in vitro functional analysis ident…

Degl'Innocenti(Debora),Alberti(Chiara),Caste… PLoS One 2011-02-18

...rev1 and five publicly available thyroid cancer datasets of gene expression on a total of 41 paired PTC/normal thyroid t...

The Werner's Syndrome protein collaborates with REV1 to promote replication for…

Phillips(Lara G),Sale(Julian E) DNA Repair (Amst) 2011-01-13

...REV1-deficient cells. Here we use the avian cell line DT40 to demonstrate that WRN assists REV1-dependent translesion sy...

Error-prone translesion synthesis mediates acquired chemoresistance.

Xie(Kun),Doles(Jason),Hemann(Michael T),Walk… Proc Natl Acad Sci U S A 2011-01-05

...Rev1, an essential TLS scaffold protein and dCMP transferase, inhibits both cisplatin- and cyclophosphamide-induced muta...

DNA polymerases and carcinogenesis.

Krutyakov(V M),Kravetskaya(T P) Biochemistry (Mosc) 2011-03-14

...Rev1, and terminal deoxynucleotidyl transferase, and only polymerases θ and σ manifest a slight 3'-exonuclease activity)...

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