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TP53 BRCA1 CRISPR single-cell cancer

Fletcher(Lynda),Yen(Tim J),Muschel(Ruth J) Radiat Res 2003-05-29

G(2) is defined as the time in the cell cycle after DNA synthesis is complete but before the initiation of mitosis. Howe...

Ouspenski(Ilia I),Van Hooser(Aaron A),Brinkl… Exp Cell Res 2003-06-09

A centromere-specific variant of histone H3, centromere protein A (CENP-A), is a critical determinant of centromeric chr...

Ditchfield(Claire),Johnson(Victoria L),Tighe… J Cell Biol 2003-06-19

The Aurora/Ipl1 family of protein kinases plays multiple roles in mitosis and cytokinesis. Here, we describe ZM447439, a...

Chen(Ee Sin),Saitoh(Shigeaki),Yanagida(Mitsu… Mol Cell 2003-03-18

CENP-A, the centromere-specific histone H3 variant, plays a crucial role in organizing kinetochore chromatin for precise...

Goshima(Gohta),Kiyomitsu(Tomomi),Yoda(Kinya)… J Cell Biol 2003-02-10

Kinetochores are the chromosomal sites for spindle interaction and play a vital role for chromosome segregation. The com...

Trazzi(Stefania),Bernardoni(Roberto),Diolait… J Struct Biol 2003-06-27

CENP-C is a fundamental component of the inner kinetochore plate and contributes to the formation of functional centrome...

Dino Rockel(Thomas),von Mikecz(Anna) J Struct Biol 2003-06-27

Although proteasomes are abundant in the nucleoplasm little is known of proteasome-dependent proteolysis within the nucl...

Knegt(A C),Li(S),Engelen(J J M),Bijlsma(E K)… Prenat Diagn 2003-10-09

An adult female patient with a history of miscarriages was found to be carrying a stable supernumerary chromosome. The p...

Mahler(M),Blüthner(M),Pollard(K M) Clin Immunol 2003-07-08

The characterization of autoantibody specificities in rheumatic diseases is important in both diagnostic and basic resea...

Craig(Jeffrey M),Wong(Lee H),Lo(Anthony W I)… EMBO J 2003-07-14

We show that Trichostatin A (TSA)-induced partial histone hyperacetylation causes a unidirectional shift in the position...

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