...REV1-deficient cells. Here we use the avian cell line DT40 to demonstrate that WRN assists REV1-dependent translesion sy...
...Rev1, failed to generate full-length lesion bypass products after 3 h. The results indicate that hPolι generates mutatio...
...REV1, and Pol ζ) have been studied extensively in vitro, but their in vivo role is only now being investigated using kno...
...Rev1, Pol ζ (Rev3/7), and Pol η (Rad30), all with human homologs. Rev1's noncatalytic role in recruiting other DNA polym...
...Rev1 and Polzeta (via Rev7). We thus suggest that PDIP38 serves as a mediator protein helping TLS Pols to transiently re...
...Rev1 foci. We propose that threshold levels of Rad53 activity exquisitely modulate the tolerance to alkylating damage at...
...Rev1, and terminal deoxynucleotidyl transferase, and only polymerases θ and σ manifest a slight 3'-exonuclease activity)...
...Rev1 incorporating the active, 5'-phosphorylated forms of tenofovir, lamivudine, emtricitabine, and zidovudine. For the ...
...REV1, a key regulator of DNA translesion synthesis at the replication fork, is required for the maintenance of repressiv...
...Rev1-targeted siRNA also abrogated UV-TLS, indicating that Rev1 is also indispensable to mutagenic TLS. Third, Polη-targ...
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