...APLP2). Differentiation was also associated with (i) a >500-fold increase in mRNA for TNF-stimulated gene-6, an essentia...
...APLP2. We found here that zinc ions bound to APP and APLP1 E2 domains and mediated their oligomerization, whereas the AP...
...APLP2) but not APP-like protein-1 (APLP1). Noteworthy, APLP2, but not APLP1, interacts with Stub1 and CRL4(CRBN), pointi...
...APLP2 in HEK293T cells we used fluorescence and surface biotinylation to quantify Fpn membrane occupancy and also measur...
...APLP2, exhibiting functions that partly overlap with those of APP. Here we tested whether APLP1 and APLP2 also show feat...
...APLP2). To rule out sampling bias as an explanation for differences in the individual datasets, a small scale quantitati...
...APLP2). Though the three proteins share similar structures and undergo the same cleavage processing by α-, β- and γ-secr...
The amyloid precursor protein (APP) and its mammalian homologs, APLP1, APLP2, have been allocated to an organellar pool ...
...APLP2)] and its orthologs (including Drosophila melanogaster, Xenopus laevis, and Caenorhabditis elegans), suggesting an...
...APLP2 single knock-outs, APP/APLP2 double knock-out, APP-swedish, APP-swedish/PS1Δexon9, and APPΔCT15) confirmed the res...
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