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Winogradoff(David),Zhao(Haiqing),Dalal(Yam... Sci Rep 2016-09-21

The centromeric nucleosome is a key epigenetic determinant of centromere identity and function. Consequently, decipherin...

McKinley(Kara L),Cheeseman(Iain M) Nat Rev Mol Cell Biol 2016-04-25

The centromere is the region of the chromosome that directs its segregation in mitosis and meiosis. Although the functio...

Martins(Nuno M C),Bergmann(Jan H),Shono(No... Mol Biol Cell 2016-11-01

Centromeres are characterized by the centromere-specific H3 variant CENP-A, which is embedded in chromatin with a patter...

Boltengagen(Mark),Huang(Anming),Boltengage... Nucleic Acids Res 2016-08-08

The incorporation of CENP-A into centromeric chromatin is an essential prerequisite for kinetochore formation. Yet, the ...

Zhang(Pingzhao),Zhang(Yuanyuan),Gao(Kun),W... Oncotarget 2016-09-26

Regulated interactions between kinetochores and spindle microtubules are critical for maintaining genomic stability duri...

Thapa(Kriti Shrestha),Oldani(Amanda),Pagli... Genetics 2016-02-08

Kinetochores are conserved protein complexes that bind the replicated chromosomes to the mitotic spindle and then direct...

Meyer(Rebecca),Faesen(Alex),Vogel(Katrin),... Small 2016-04-05

Large supramolecular protein complexes, such as the molecular machinery involved in gene regulation, cell signaling, or ...

Rago(Florencia),Gascoigne(Karen E),Cheesem... Curr Biol 2016-01-14

The kinetochore provides a vital connection between chromosomes and spindle microtubules [1, 2]. Defining the molecular ...

Ohta(Shinya),Wood(Laura),Toramoto(Iyo),Yag... Mol Biol Cell 2016-04-19

Centrosomes nucleate spindle formation, direct spindle pole positioning, and are important for proper chromosome segrega...

Singh(Ragini),Singh(Sanjay) Colloids Surf B Biointerfac... 2016-03-25

...CeNPs (3+) and CeNPs (4+) have been shown to exhibit superoxide dismutase (SOD) and catalase mimetic activity, respectiv...