Literature Search

Li(Wen),Xu(Zhi-Liang) Zhongguo Dang Dai Er Ke Za Zhi 2015-09-10

...RAD50 gene were determined using PCR-RFLP, and the relationship of the RAD50 polymorphism with ALL susceptibility and cl...

Xie(Maohua),Park(Dongkyoo),You(Shuo),Li(Rui)… Nucleic Acids Res 2015-05-01

...Rad50/NBS1)-mediated resection of DSB ends is a required step in preparing for DSB repair via the HR DNA repair pathway....

Ouyang(Jian),Garner(Elizabeth),Hallet(Alexan… Mol Cell 2015-04-06

...RAD50-NBS1, and TRF2. Thus, the interactions of SLX4 with SUMO and ubiquitin increase its affinity for factors recognizi...

Gray(Kelly),Kumar(Sheetal),Figg(Nichola),Har… Circ Res 2015-04-22

...RAD50/NBS1 complex that senses DSB repair. Oxidative stress-induced DSBs were increased in plaque VSMCs, but DSB repair ...

Paull(Tanya T) Annu Rev Biochem 2015-12-17

...Rad50-Nbs1 (MRN) complex and other factors at sites of DNA breaks. In addition, oxidation of ATM activates the kinase in...

Andres(Sara N),Appel(C Denise),Westmoreland(… Nat Struct Mol Biol 2015-04-08

...Rad50-Nbs1 to initiate repair of DNA double-strand breaks (DSBs), but its functions remain enigmatic. We report that tet...

Czarny(Piotr),Pawlowska(Elzbieta),Bialkowska… Int J Mol Sci 2015-09-25

...Rad50-Nbs1 (MRN) complex or FOXO3, which activate repressors of mTORC1. SQSTM1/p62 is one of the proteins whose levels a...

Sarangi(Prabha),Steinacher(Roland),Altmannov… PLoS Genet 2015-06-29

...Rad50-Xrs2 complex, further increases end resection. These findings reveal a novel role for sumoylation in DNA repair by...

Ferrari(Matteo),Dibitetto(Diego),De Gregorio… PLoS Genet 2015-06-30

...Rad50-Xrs2 nuclease complex, together with Sae2, initiates the 5'-to-3' resection of Double-Strand DNA Breaks (DSBs). Ex...

Dai(Xiaofeng),Fagerholm(Rainer),Khan(Sofia),… Breast Cancer Res Treat 2015-09-28

...RAD50 gene is a common event particularly in basal-like breast cancer, and often occurs together with deletions of BRCA1...