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Virtual Pharmacophore Screening Identifies Small-Molecule Inhibitors of the Rev…

Dash(RC),Ozen(Z),McCarthy(KR),Chatterjee(N),… ChemMedChem 2019-00-04

...Rev1 (Rev1-CT) and the Rev1 interacting regions (RIR) of other TLS DNA polymerases. To continue the identification of sm...

Oncogene homologue Sch9 promotes age-dependent mutations by a superoxide and Re…

Madia(F),Wei(M),Yuan(V),Hu(J),Gattazzo(C),Ph… J Cell Biol 2009-08-24

...REV1 expression and translesion synthesis, and elevated resistance to oxidative stress-induced mutagenesis. Deletion of ...

Saccharomyces cerevisiae polymerase zeta functions in mitochondria.

Zhang(H),Chatterjee(A),Singh(KK) Genetics 2006-04-00

...Rev1 proteins participate in the mitochondrial DNA mutagenesis. Supporting this evidence, both polymerase zeta and Rev1p...

Human Rev1 polymerase disrupts G-quadruplex DNA.

Eddy(Sarah),Ketkar(Amit),Zafar(Maroof K),Mad… Nucleic Acids Res 2014-05-19

...Rev1 (hRev1) disrupts G4 DNA structures and prevents refolding in vitro. Nucleotidyl transfer by hRev1 is not necessary ...

Rev1 contributes to proper mitochondrial function via the PARP-NAD+-SIRT1-PGC1α…

Fakouri(NB),Durhuus(JA),Regnell(CE),Angleys(… Sci Rep 2017-00-02

...Rev1, have the ability to bypass some DNA lesions, which can circumvent the process leading to replication fork arrest a...

Comparative efficacy of daptomycin and vancomycin in the therapy of experimenta…

Vaudaux(P),Francois(P),Bisognano(C),Li(D),Le… J Antimicrob Chemother 2003-07-00

...Rev1 were 1-2 and 2-4 or 1 and 2 mg/L, respectively. In vitro elimination of strain Rev1 in the presence of 50% tissue c...

DNA polymerase ζ is a major determinant of resistance to platinum-based chemoth…

Sharma(Shilpy),Shah(Nicholas A),Joiner(Ariel… Mol Pharmacol 2012-07-16

...REV1, and Polζ. Because oxaliplatin, satraplatin, and picoplatin contain bulkier chemical groups attached to the platinu...

The Werner's Syndrome protein collaborates with REV1 to promote replication for…

Phillips(LG),Sale(JE) DNA Repair (Amst) 2010-10-05

...REV1-deficient cells. Here we use the avian cell line DT40 to demonstrate that WRN assists REV1-dependent translesion sy...

The Oligomeric State of Rad6-Rad18 and Its Interactions with Translesion Synthe…

Woodward(TJ),Ripley(BM),Ling(JA),Washington(… Biomolecules 2026-08-12

Translesion synthesis is a major DNA damage bypass pathway in which specialized DNA polymerases, such as pol η and Rev1,...

Involvement of specialized DNA polymerases in mutagenesis by 8-hydroxy-dGTP in …

Satou(K),Hori(M),Kawai(K),Kasai(H),Harashima… DNA Repair (Amst) 2009-05-01

...REV1 plus DNA pol zeta (but not by that of DNA pol eta plus REV1), suggesting that REV1-DNA pol eta and DNA pol zeta wor...

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