During mitosis, cells undergo massive deformation and reorganization, impacting on all cellular structures. Mitochondria...
Centromeres control genetic inheritance by directing chromosome segregation but are not genetically encoded themselves. ...
Centromere protein B (CENP-B) is one of the major proteins involved in centromere formation, binding to centromeric repe...
The presence of chromatin containing the histone H3 variant CENP-A dictates the location of the centromere in a DNA sequ...
The CENP-T/-W histone fold complex, as an integral part of the inner kinetochore, is essential for building a proper kin...
Heterochromatin is incompatible with centromeric chromatin assembly and propagation. In this issue of Developmental Cell...
Centromere chromatin containing histone H3 variant CENP-A is required for accurate chromosome segregation as a foundatio...
Repetitive DNA sequences, comprising up to 50 % of the genome in all eukaryotes, play important roles in a wide range of...
Hutchinson-Gilford progeria syndrome (HGPS, OMIM 176670) is a rare premature aging disorder that leads to death at an av...
Aneuploidy, an abnormal chromosome number that deviates from a multiple of the haploid, has been recognized as a common ...
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