Accurate chromosome segregation in mammalian cells is guided by the centromere, a specialized chromosome region defined ...
Cerium oxide nanoparticles (CeNPs) neutralize reactive oxygen and nitrogen species. Since oxidative stress plays a role ...
We sought to evaluate whether scleroderma patients who are double-positive for anti-interferon inducible protein 16 (IFI...
Uncontrolled propagation of retrotransposons is potentially detrimental to host genome integrity. Therefore, cells have ...
All eukaryotic genomes are packaged into basic units of DNA wrapped around histone proteins called nucleosomes. The abil...
Transcription at the centromere of chromosomes plays an important role in kinetochore assembly in many eukaryotes, and n...
Heterochromatin is incompatible with centromeric chromatin assembly and propagation. In this issue of Developmental Cell...
Centromere chromatin containing histone H3 variant CENP-A is required for accurate chromosome segregation as a foundatio...
Repetitive DNA sequences, comprising up to 50 % of the genome in all eukaryotes, play important roles in a wide range of...
The CENP-T/-W histone fold complex, as an integral part of the inner kinetochore, is essential for building a proper kin...
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