Centromeres control genetic inheritance by directing chromosome segregation but are not genetically encoded themselves. ...
Centromere protein B (CENP-B) is one of the major proteins involved in centromere formation, binding to centromeric repe...
The presence of chromatin containing the histone H3 variant CENP-A dictates the location of the centromere in a DNA sequ...
The CENP-T/-W histone fold complex, as an integral part of the inner kinetochore, is essential for building a proper kin...
Heterochromatin is incompatible with centromeric chromatin assembly and propagation. In this issue of Developmental Cell...
Centromere chromatin containing histone H3 variant CENP-A is required for accurate chromosome segregation as a foundatio...
Repetitive DNA sequences, comprising up to 50 % of the genome in all eukaryotes, play important roles in a wide range of...
Hutchinson-Gilford progeria syndrome (HGPS, OMIM 176670) is a rare premature aging disorder that leads to death at an av...
Aneuploidy, an abnormal chromosome number that deviates from a multiple of the haploid, has been recognized as a common ...
Microtubule (MT)-binding centromere protein F (CENP-F) was previously shown to play a role exclusively in chromosome seg...
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