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CCS and SOD1 mRNA are reduced after copper supplementation in peripheral mononu…

Suazo(M),Olivares(F),Mendez(MA),Pulgar(R),Pr… J Nutr Biochem 2008-04-00

...APLP2), Cu/Zn superoxide dismutase (SOD1) and its copper chaperone (CCS) in peripheral mononuclear cells (PMNCs) from he...

The Role of the anti-amyloidogenic secretase ADAM10 in shedding the APP-like pr…

Endres(K),Fahrenholz(F) Curr Alzheimer Res 2012-02-00

...APLP2 and APP-L - a shedding by ADAM10 has been demonstrated in vivo. In addition, the importance of these proteins, esp...

Clioquinol mediates copper uptake and counteracts copper efflux activities of t…

Treiber(C),Simons(A),Strauss(M),Hafner(M),Ca… J Biol Chem 2004-12-10

...APLP2 extracellular domains but not the extracellular domain of APLP1 decreased intracellular copper levels. The express...

A genome-wide screen for depression in two independent Dutch populations.

Schol-Gelok(S),Janssens(AC),Tiemeier(H),Liu(… Biol Psychiatry 2010-07-15

...APLP2 gene on chromosome 11q25. Our linkage and association studies suggest a locus for depression on chromosomes 2p16.1...

Immuno-histochemical correlation of fibrosis-related markers with the desmoplas…

Bösch(F),Altendorf-Hofmann(A),Koliogiannis(V… J Cancer Res Clin Oncol 2023-05-00

...APLP2, BNIP3L, CD59, DKK3) were investigated in primary tumors of 128 siNENs. The expression levels were correlated with...

Improved Lysosomal Trafficking Can Modulate the Potency of Antibody Drug Conjug…

DeVay(RM),Delaria(K),Zhu(G),Holz(C),Foletti(… Bioconjug Chem 2017-00-19

...APLP2 mediates cell killing, both in vitro and in vivo, more effectively than an ADC against Trop2, a protein with less ...

Survival of cultured neurons from amyloid precursor protein knock-out mice agai…

White(AR),Zheng(H),Galatis(D),Maher(F),Hesse… J Neurosci 1998-08-15

...APLP2) molecules and supports the theory that APP and the APLPs may have similar functional activities. Increased expres...

Lack of APLP1 leads to subtle alterations in neuronal morphology but does not a…

Erdinger(S),Amrein(I),Back(M),Ludewig(S),Kor… Front Mol Neurosci 2022-00-00

...APLP2, that all constitute synaptic adhesion proteins. While APP and APLP2 are ubiquitously expressed, APLP1 is specific...

Diazinon-induced Cognitive Impairment: Alternations in Amyloid Precursor Protei…

Sarailoo(M),Afshari(S),Asghariazar(V),Niri(M… Curr Top Med Chem 2025-00-00

...APLP2), and amyloid-β (Aβ) via western blotting and ELISA. Real-time quantitative PCR was performed to evaluate the expr...

JNK-interacting protein-1 promotes transcription of A beta protein precursor bu…

Scheinfeld(MH),Matsuda(S),D'Adamio(L) Proc Natl Acad Sci U S A 2003-02-18

...APLP2 (for amyloid beta precursor-like protein) can cause activation in combination with Fe65, APLP1 and APLP2 show litt...

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