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TP53 BRCA1 CRISPR single-cell cancer

Liu(Yahui),Petrovic(Arsen),Rombaut(Pascali... Open Biol 2016-11-04

Accurate chromosome segregation during mitosis and meiosis is crucial for cellular and organismal viability. Kinetochore...

Freitag(Michael) Mycologia 2016-08-08

...CENPs). CENP-A, sometimes called centromere-specific H3 (CenH3), is incorporated into nucleosomes within or near centrom...

Wood(Laura),Booth(Daniel G),Vargiu(Giulia)... Open Biol 2016-10-07

Most studies using knockout technologies to examine protein function have relied either on shutting off transcription (c...

Beh(Thian T),MacKinnon(Ruth N),Kalitsis(Paul) Mol Cytogenet 2016-03-25

The centromere plays a crucial role in ensuring the fidelity of chromosome segregation during cell divisions. However, i...

Kral(Leos) F1000Res 2016-04-29

The centromeric protein CENP-C is a base component of the kinetochore. This protein, along with CENP-A has been shown to...

Zasadzińska(Ewelina),Foltz(Daniel R) Dev Cell 2016-08-24

Centromeres of higher eukaryotes are defined by the epigenetic inheritance of the centromere-specific CENP-A nucleosome....

Rosin(Leah),Mellone(Barbara G) Dev Cell 2016-09-01

Centromeres mediate the conserved process of chromosome segregation, yet centromeric DNA and the centromeric histone, CE...

Matsumura(Kensuke),Nakazawa(Takanobu),Naga... J Mol Psychiatry 2016-04-22

A spontaneous de novo mutation is a new mutation appeared in a child that neither the parent carries. Recent studies sug...

Kwenda(Lucretia),Collins(Caitriona M),Datt... Development 2016-09-06

The centromere-specific histone CENP-A is the key epigenetic determinant of centromere identity. Whereas most histones a...

Cerutti(Federico),Gamba(Riccardo),Mazzagat... Mol Cytogenet 2016-04-28

The centromere is the specialized locus required for correct chromosome segregation during cell division. The DNA of mos...

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