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Mec1 and Rad53 inhibit formation of single-stranded DNA at telomeres of Sacchar…

Jia(Xindan),Weinert(Ted),Lydall(David) Genetics 2004-11-02

...Rad17, Mec3, as well as Rad24, members of the putative checkpoint clamp loader (Rad24) and sliding clamp (Rad17, Mec3) c...

Requirement for ATP by the DNA damage checkpoint clamp loader.

Majka(Jerzy),Chung(Brian Y),Burgers(Peter M … J Biol Chem 2004-07-21

...Rad17, Mec3, and Ddc1 (Rad17/3/1) onto partial duplex DNA in an ATP-dependent manner. Interactions between the clamp loa...

ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ion…

Stiff(Tom),O'Driscoll(Mark),Rief(Nicole),Iwa… Cancer Res 2004-05-19

...Rad17. However, by phosphorylating H2AX, DNA-PK can contribute to the presence of the damage response proteins MDC1 and ...

Mutation of the mouse Rad17 gene leads to embryonic lethality and reveals a rol…

Budzowska(Magda),Jaspers(Iris),Essers(Jeroen… EMBO J 2004-10-06

...Rad17, the mouse homolog of the Schizosaccharomyces pombe Rad17 checkpoint clamp-loader component, resulted in embryonic...

Human immunodeficiency virus type 1 Vpr-mediated G2 arrest requires Rad17 and H…

Zimmerman(Erik S),Chen(Junjie),Andersen(Josh… Mol Cell Biol 2004-12-03

...Rad17 and Hus1 to induce G(2) arrest as well as Vpr-induced phosphorylation of histone 2A variant X (H2AX) and formation...

Requirement of the Mre11 complex and exonuclease 1 for activation of the Mec1 s…

Nakada(Daisuke),Hirano(Yukinori),Sugimoto(Ka… Mol Cell Biol 2004-12-06

...Rad17 complex associates with sites of DNA damage and modulates the Mec1 signaling pathway. However, Ddc1 association wi...

Robust G1 checkpoint arrest in budding yeast: dependence on DNA damage signalin…

Gerald(Jonathan N Fitz),Benjamin(Jacqueline … J Cell Sci 2003-01-07

...rad17 and rad24 mutants are completely arrest deficient. Distinct from gamma irradiation, G1 arrest after UV is RAD14 de...

Clamp and clamp loader structures of the human checkpoint protein complexes, Ra…

Shiomi(Yasushi),Shinozaki(Ayako),Nakada(Dais… Genes Cells 2003-03-25

...Rad17-RFCs2-5 (Rad17-RFC), have been predicted to function as novel clamp and clamp loader proteins, respectively, due t...

Telomere binding of checkpoint sensor and DNA repair proteins contributes to ma…

Nakamura(Toru M),Moser(Bettina A),Russell(Pa… Genetics 2003-02-27

...Rad17, Rad26, Hus1, Crb2, Chk1, Cds1), Tel1, a telomere-binding protein (Taz1), and DNA repair proteins (Ku70, Rad32), w...

The human checkpoint Rad protein Rad17 is chromatin-associated throughout the c…

Post(Sean M),Tomkinson(Alan E),Lee(Eva Y-H P) Nucleic Acids Res 2003-10-20

The checkpoint Rad proteins Rad17, Rad9, Rad1, Hus1, ATR, and ATRIP become associated with chromatin in response to DNA ...

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