Alzheimer's disease (AD) is a complicated multifactorial syndrome. Lessons have been learned through failed clinical tri...
Centromeres are responsible for the correct segregation of chromosomes during mitosis and meiosis. Holocentric chromosom...
The kinetochore connects chromosomes to microtubules during mitosis and therefore plays an essential role in faithful ch...
The Arabidopsis separase homolog, AtESP, associates with microtubules and affects cell polarity but does not bind microt...
Microtubules play an essential role in breaking cellular symmetry. We have previously shown that separase associates wit...
Defects in AU-rich elements (ARE)-mediated posttranscriptional control can lead to several abnormal processes that under...
The Mis18 complex specifies the site of new CENP-A nucleosome assembly by recruiting the CENP-A-specific assembly factor...
Centromeres of higher eukaryotes are epigenetically defined by centromere protein A (CENP-A), a centromere-specific hist...
Kenneth Rempher, PhD, MBA, CENP, RN, is the chief nursing officer for the University of Iowa (UI) Hospitals and Clinics....
Histone proteins are essential for the organization, expression, and inheritance of genetic material for eukaryotic cell...
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