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EGFR TKIs suppress MUC1 glycosylation through the PI3K/AKT/SP1/C1GALT1 pathway …

Zhou(Z),Chen(S),Zhao(J),Du(X),Yin(H),Zhou(C)… Cell Rep Med 2025-07-15

...C1GALT1) identified as a key enzyme downregulated by EGFR TKIs, suggesting C1GALT1 as a potential therapeutic target.

Production of recombinant IgA1 with defined mucin-type O-glycans in Nicotiana t…

Bailly(N),Grünwald-Gruber(C),Peeters(M),Chau… Front Plant Sci 2025-00-00

...C1GalT1 to form the core 1 structure. Human IgA1 was produced in these engineered BY-2 cell lines and the presence of mu...

SOCS1 improves abnormal IgA galactosylation in IgA nephropathy by regulating th…

Huang(Y),Wang(Q),Lin(C),Qiu(B),Chen(S),Wang(… Immunol Res 2025-08-04

...C1GALT1 in PBMC from IgAN patients was decreased and positively correlated with SOCS1 expression, while the expressions ...

Rosmarinic acid influences the expression of glycoforms in DLD-1 and HT-29 colo…

Radziejewska,Czerwińska(K),Popławska(B),Gali… Biomed Pharmacother 2025-09-00

...C1GalT1, Cosmc, ST3GalT1, FUT3/4, Gal-3, and Akt mRNAs. ST6GalNAcT1 mRNA was suppressed by both RA concentrations in DLD...

Sialyl-T Antigen: A Novel Red Blood Cell Determinant for Plasmodium falciparum …

Mikdar(M),Shabani(E),Grüring(C),Chaand(M),Ka… Am J Hematol 2025-11-00

...C1GALT1) as a novel host determinant for P. falciparum invasion. Analyses of C1GALT1-deficient cultured reticulocytes an...

Pathogenic glycosyltransferase genes and potential therapeutic drugs in pressur…

Wu(J),Lu(Y),Gao(X),Hu(X),Lu(Z),Li(C) ESC Heart Fail 2025-12-00

...C1galt1, Extl2 and Pigh. Pearson correlation analysis revealed that 11 GTGs were significantly associated with pathologi...

Association between C1GALT1 variants and genetic susceptibility to IgA nephropa…

Li(W L),Lu(C) Genet Mol Res 2016-04-11

...C1GalT1). To evaluate the association between C1GalT1 single nucleotide polymorphisms (SNPs) and IgAN, we performed a ca...

Up-regulation of C1GALT1 promotes breast cancer cell growth through MUC1-C sign…

Chou(Chih-Hsing),Huang(Miao-Juei),Chen(Chi-H… Oncotarget 2016-02-29

...C1GALT1 in breast cancer malignant phenotypes. Public databases and our data showed that C1GALT1 mRNA and C1GALT1 protei...

Molecular analysis of the cumulus matrix: insights from mice with O-glycan-defi…

Ploutarchou(Panayiota),Melo(Pedro),Day(Antho… Reproduction 2016-01-12

...C1galt1 Mutant (C1galt1(FF):ZP3Cre) and Control (C1galt1(FF)) mice to investigate how cumulus expansion is affected by o...

Relevance of βGal-βGalNAc-containing glycans and the enzymes involved in their …

Milde-Langosch(Karin),Schütze(Dina),Oliveira… Breast Cancer Res Treat 2016-02-24

...C1GALT1 protein correlated significantly with shorter OAS. Notably, combined overexpression of C1GALT1/GALNT1 or C1GALT1...

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