Centromeres are comprised of long stretches of repetitive DNA that evolve rapidly in organisms across the tree of life. ...
...CENPE), signaling and metabolism (SHIP1, GAK, ABCD4), chromatin regulation (BRD4, MAGEB4), and testicular architecture (...
...CENPE) and hyperactive immunity (upregulated NLRP3/IL23R) impairing alveolar/capillary development; 3) suppressed circad...
Chromosomal instability is a common feature of malignancies that arises from persistent defects in chromosome segregatio...
Centromere protein A (CENP-A), a centromeric histone H3 variant highly expressed in aggressive cancers, promotes epithel...
...CENPE is the only common gene and can be used as a prognostic gene of BCR. Cell-based assays validated that CENPF promot...
The mammalian kinetochore connects chromosomes to dynamic spindle microtubules. To remain attached, it must maintain str...
Centromeres are chromosomal loci required for accurate chromosome segregation in cell division and are defined epigeneti...
Objective: Patients with systemic lupus erythematosus (SLE) exhibit elevated malignancy risk, with increased bladder can...
Accurate chromosome segregation requires kinetochores to form robust, load-bearing attachments to dynamic spindle microt...
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