...SMARCA4-deficient thoracic undifferentiated tumor, atypical carcinoid, and adenoid cystic carcinoma. Notably, the highly...
...SMARCA4 mutation. The patient completed four cycles of adjuvant vinblastine, cisplatin, cyclophosphamide, bleomycin, dox...
SMARCA4-deficient non-small cell lung cancer (SMARCA4-dNSCLC) represents a distinct, highly aggressive molecular subtype...
...SMARCA4). The genetic changes included GOF mutations (KRAS, BRAF genes, etc.), LOF mutations (STAG1, SMARCA2 genes, etc....
...SMARCA4, are known to cause CSS with variable phenotype expression. The expanded use of genotype-first methods has contr...
...SMARCA4, while the NAS-low state showed immune-regulatory features. Functional assays confirmed that SERPINE2 knockdown ...
...SMARCA4 to enhance transcriptional accessibility. Furthermore, RBM22 is essential for the gene-specific recruitment of R...
...SMARCA4-deficient cancers, including SMARCA4-deficient sinonasal carcinomas, and most sinonasal teratocarcinosarcomas. T...
...SMARCA4/2-deficient SCCOHT and NSCLC cells but not in SMARCA4/2-proficient controls. Mechanistically, SMARCA4/2 directly...
...SMARCA4, KMT2A, and ARID1A. No hotspot mutation sites in NRG1 were found. The overall objective response rate of all NRG...
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