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Retention but not recruitment of Crb2 at double-strand breaks requires Rad1 and…

Du(Li-Lin),Nakamura(Toru M),Moser(Bettina A)… Mol Cell Biol 2003-09-24

...Rad17 complexes, but these foci do not persist as long as in wild-type cells. Our results suggest that Crb2 functions at...

Claspin, a Chk1-regulatory protein, monitors DNA replication on chromatin indep…

Lee(Joon),Kumagai(Akiko),Dunphy(William G) Mol Cell 2003-04-02

...Rad17 require RPA for association with DNA. Claspin, ATR, and Rad17 all bind to chromatin independently. These findings ...

Ionizing irradiation effects on S-phase in checkpoint mutants of the yeast Sacc…

King(William R),Rowley(Roy),Schroeder(Alice … Curr Genet 2003-11-26

...RAD17, RAD24, RAD53, MEC1 and MEC3. However, at least four, RAD17, RAD53, MEC1, MEC3, are not needed to delay S-phase pr...

Hrad17 expression in thymoma.

Sasaki(Hidefumi),Kobayashi(Yoshihiro),Yukiue… Jpn J Thorac Cardiovasc Surg 2003-05-30

...rad17 (Hrad17), from colon cancer tissue. The loss of checkpoint control in mammalian cells results in genomic instabili...

Regulation of Chk1 includes chromatin association and 14-3-3 binding following …

Jiang(Kecheng),Pereira(Elizabeth),Maxfield(M… J Biol Chem 2003-08-18

...Rad17 and Hus1. We show that Chk1 is associated with chromatin in cycling cells and that the chromatin-associated Chk1 i...

Telomeric position effect variegation in Saccharomyces cerevisiae by Caenorhabd…

Jedrusik(Monika A),Schulze(Ekkehard) Mol Cell Biol 2003-06-12

...RAD17) for their influence on repeat-dependent transgene silencing for C. elegans.

Genomic instability and endoreduplication triggered by RAD17 deletion.

Wang(Xin),Zou(Lee),Zheng(Huyong),Wei(Qingyi)… Genes Dev 2003-05-15

...Rad17, a component of the checkpoint clamp loader complex (Rad17/Rfc2-5), is required for the response to DNA damage and...

Correlation between checkpoint activation and in vivo assembly of the yeast che…

Giannattasio(Michele),Sabbioneda(Simone),Min… J Biol Chem 2003-08-21

Rad17-Mec3-Ddc1 forms a proliferating cell nuclear antigen-like complex that is required for the DNA damage response in ...

Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp …

Bermudez(Vladimir P),Lindsey-Boltz(Laura A),… Proc Natl Acad Sci U S A 2003-04-01

...Rad17-replication factor C (Rad17-RFC) and the Rad9-Rad1-Hus1 (9-1-1) checkpoint complex, are thought to be involved in ...

Checkpoint activation regulates mutagenic translesion synthesis.

Kai(Mihoko),Wang(Teresa S-F) Genes Dev 2003-01-30

...Rad17 or translesion synthesis polymerases DinB and Polzeta. Cells respond to genomic perturbation by up-regulation of D...

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