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Proteins responsible for anticentromere activity found in the sera of patients …

Kremer(L),Alvaro-Gracia(J M),Ossorio(C),Avil… Clin Exp Immunol 1988-11-17

Anticentromere antibodies (ACA) present in a high percentage of patients with complete or incomplete CREST scleroderma, ...

Kinetochore appearance during meiosis, fertilization and mitosis in mouse oocyt…

Schatten(G),Simerly(C),Palmer(D K),Margolis(… Chromosoma 1988-10-06

The events of mammalian fertilization overlap with the completion of meiosis and first mitosis; the pro-nuclei never fus...

Tubulin interaction with kinetochore proteins: analysis by in vitro assembly an…

Balczon(R D),Brinkley(B R) J Cell Biol 1987-09-29

The sera from patients with the CREST (calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, telangie...

Mammalian kinetochore/centromere composition: a 50 kDa antigen is present in th…

Kingwell(B),Rattner(J B) Chromosoma 1987-12-31

The composition of the mammalian kinetochore/centromere was studied by indirect immunofluorescence and immunoblotting pr...

A 17-kD centromere protein (CENP-A) copurifies with nucleosome core particles a…

Palmer(D K),O'Day(K),Wener(M H),Andrews(B S)… J Cell Biol 1987-05-08

We have detected and begun to characterize a 17-kD centromere-specific protein, CENP-A (Earnshaw, W. C., and N. Rothfiel...

Analysis of anticentromere autoantibodies using cloned autoantigen CENP-B.

Earnshaw(W C),Machlin(P S),Bordwell(B J),Rot… Proc Natl Acad Sci U S A 1987-08-20

A cDNA clone encoding CENP-B, the 80-kDa human centromere autoantigen, was used to construct a panel of hybrid proteins ...

Molecular cloning of cDNA for CENP-B, the major human centromere autoantigen.

Earnshaw(W C),Sullivan(K F),Machlin(P S),Coo… J Cell Biol 1987-05-08

We have isolated a series of overlapping cDNA clones for approximately 95% of the mRNA that encodes CENP-B, the 80-kD hu...

Three human chromosomal autoantigens are recognized by sera from patients with …

Earnshaw(W),Bordwell(B),Marino(C),Rothfield(… J Clin Invest 1986-03-26

We have identified 39 individuals with anti-centromere antibodies (ACA) in our patient population, all of whom have Rayn...

Identification of a family of human centromere proteins using autoimmune sera f…

Earnshaw(W C),Rothfield(N) Chromosoma 1985-05-08

We have examined "preimmune" serum samples from a patient who progressively developed the symptoms of scleroderma CREST ...

Three related centromere proteins are absent from the inactive centromere of a …

Earnshaw(W C),Migeon(B R) Chromosoma 1985-11-20

We developed an aqueous spreading procedure that permits simultaneous analysis of human chromosomes by Q-banding and ind...

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