Anticentromere antibodies (ACA) present in a high percentage of patients with complete or incomplete CREST scleroderma, ...
The events of mammalian fertilization overlap with the completion of meiosis and first mitosis; the pro-nuclei never fus...
The sera from patients with the CREST (calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, telangie...
The composition of the mammalian kinetochore/centromere was studied by indirect immunofluorescence and immunoblotting pr...
We have detected and begun to characterize a 17-kD centromere-specific protein, CENP-A (Earnshaw, W. C., and N. Rothfiel...
A cDNA clone encoding CENP-B, the 80-kDa human centromere autoantigen, was used to construct a panel of hybrid proteins ...
We have isolated a series of overlapping cDNA clones for approximately 95% of the mRNA that encodes CENP-B, the 80-kD hu...
We have identified 39 individuals with anti-centromere antibodies (ACA) in our patient population, all of whom have Rayn...
We have examined "preimmune" serum samples from a patient who progressively developed the symptoms of scleroderma CREST ...
We developed an aqueous spreading procedure that permits simultaneous analysis of human chromosomes by Q-banding and ind...
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